Leptin Receptor 抗体 (Biotin)
Quick Overview for Leptin Receptor 抗体 (Biotin) (ABIN668260)
抗原
See all Leptin Receptor (LEPR) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from sheep Leptin R
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Leptin Receptor (LEPR)
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别名
- Leptin receptor/Ob-R
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背景
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Synonyms: obl, CD 295, CD295, CD295 antigen, Db, Fa, HuB219, LEP R, LEPR, LEPROT, Leptin receptor fatty, Leptin receptor gene related protein, Leptin receptor precursor, OB R, OB R gene related protein, OB receptor, OB-RGRP, Obr.
Background: Leptin receptor (OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. An OB-R transcript encodes a soluble form of the receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist. Human OB-R encodes a 1 165 amino acid residue precursor protein with a 22 amino acid residue signal peptide, an 816 amino acid residue extracellular domain, a 21 amino acid residue transmembrane domain and a 303 amino acid residue cytoplasmic domain.
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分子量
- 13kDa
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途径
- JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
抗原
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