GABRG2 抗体
Quick Overview for GABRG2 抗体 (ABIN6658275)
抗原
See all GABRG2 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 112-401-c81
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Supplier
- Rockland
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原理
- GABA(A) Receptor gamma 2 Antibody
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交叉反应 （详细）
- Anti-GABA(A) Receptor gamma 2 Antibody is directed against rat GABA(A) Receptor gamma 2.
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纯化方法
- The antibody was prepared from monospecific neat serum.
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免疫原
- Anti-GABA(A) Receptor gamma 2 Antibody was produced by repeated immunizations with rat GABA(A) Receptor gamma 2- Synthetic peptide corresponding to amino acid residues specific to the gamma 2 subunit.
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亚型
- IgG
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anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (pSer327) antibody
GABRG2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 41-140) antibodyGABRG2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (N-Term) antibodyGABRG2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 170-270) antibodyGABRG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 198-224) antibodyGABRG2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB23939 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) antibodyGABRG2 适用: 人, 小鼠, 大鼠 IP, ICC 宿主: 小鼠 Monoclonal 331A12 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 198-224) antibodyGABRG2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 42-108) antibodyGABRG2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 61-110) antibodyGABRG2 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, Pig, 马, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (N-Term) antibodyVerified GABRG2 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:400
Western_Blot_Dilution: 1:1000
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说明
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Anti-GABA(A) Receptor gamma 2 (Rabbit) antibody has been tested in Western Blotting and IHC. Expect a band of approximately 46kDa in size corresponding γ2-subunit of the GABAA receptor in Western blots of rat brain extracts. Specific conditions should by optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
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别名
- GABA(A) Receptor gamma 2
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背景
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Synonyms: rabbit anti-GABA(A) Receptor gamma 2 Antibody, Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, Gabrg2
Background: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) sub-type. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six αs, four βs and four γs, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for α- and β-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, co-expression of a γ-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor. Phosphorylation of β-subunits of the receptor has been shown to modulate GABAA-R function. Anti-GABA(A) Receptor gamma 2 antibody is ideal for investigators involved in Neuroscience.
Gene Name: GABRG2
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基因ID
- 29709
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NCBI登录号
- NP_899156
抗原
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