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SYT1 抗体 (pThr202)

Rockland 612-401-e38 SYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN6658256
Supplier Product No.: 612-401-e38
发货至: 中国
  • 抗原 See all SYT1 抗体
    SYT1 (Synaptotagmin I (SYT1))
    抗原表位
    • 15
    • 14
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr202
    适用
    • 80
    • 69
    • 48
    • 11
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 91
    • 12
    • 6
    • 1
    • 1
    • 1
    克隆类型
    • 100
    • 12
    多克隆
    标记
    • 67
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYT1 antibody is un-conjugated
    应用范围
    • 67
    • 41
    • 36
    • 16
    • 13
    • 13
    • 13
    • 11
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Supplier Product No.
    612-401-e38
    Supplier
    Rockland
    原理
    Synaptotagmin phospho T202 Antibody
    交叉反应 (详细)
    Anti-Synaptotagmin 1 pT202 Antibody is directed against rat Synaptotagmin 1 phosphorylated at T202 residue.
    纯化方法
    Synaptotagmin antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
    免疫原
    Anti-Synaptotagmin pT202 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Thr202 of synaptotagmin.
    亚型
    IgG
    Top Product
    Discover our top product SYT1 Primary Antibody
  • 应用备注

    Immunohistochemistry_Dilution: 1:400

    Western_Blot_Dilution: 1:1000

    说明

    Anti-Synaptotagmin pT202 (Rabbit) antibody is tested for use in Western Blotting and ICC. Expect a band of approximately 60-62 kDa in size corresponding to synaptotagmin protein phosphorylated at Thr202 in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    SYT1 (Synaptotagmin I (SYT1))
    别名
    Syt1 (SYT1 产品)
    背景

    Synonyms: SytI, p65

    Background: Synaptotagmin 1 pT202 Antibody detects Synaptotagmin 1, which is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS. It is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Recent studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion. It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size. Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission. Anti-Synaptotagmin 1 pT202 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

    Gene Name: SYT1

    基因ID
    25716
    UniProt
    P21707
    途径
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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