Synaptojanin 1 抗体 (C-Term)
Quick Overview for Synaptojanin 1 抗体 (C-Term) (ABIN6658254)
抗原
See all Synaptojanin 1 (SYNJ1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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Supplier Product No.
- 212-301-e35
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Supplier
- Rockland
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原理
- Synaptojanin 1 Antibody
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交叉反应 （详细）
- Anti-Synaptojanin 1 Monoclonal Antibody is directed against rat synaptojanin 1
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纯化方法
- .Synaptojanin 1 antibody was Protein G purified from cell culture supernatant.
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免疫原
- Anti-Synaptojanin 1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant protein from the C-terminal region of rat synaptojanin 1.
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亚型
- IgG1
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anti-Synaptojanin 1 (SYNJ1) (AA 1030-1261) antibody
SYNJ1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (N-Term) antibodySYNJ1 适用: 人, 大鼠, 小鼠, Pig, 犬, 豚鼠, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1474-1573) antibodySYNJ1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A2 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 481-580) antibodySYNJ1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1148-1182), (C-Term) antibodySYNJ1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB53251 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1517-1551), (C-Term) antibodySYNJ1 适用: 人 WB 宿主: 兔 Polyclonal RB52973 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1474-1573) antibodySYNJ1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1190-1239) antibodySYNJ1 适用: 人, Pig, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 147-196) antibodySYNJ1 适用: 人, Pig, 马, 兔, Cow, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) antibodySYNJ1 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:1000
Western_Blot_Dilution: 1:1000
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说明
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Anti-Synaptojanin 1 antibody is tested for use in Western Blotting and IHC. Expect a band of approximately 145 kDa in size corresponding to synaptojanin I proteins of rat brain extracts. Researchers should determine optimal titers for applications that are not stated below.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- Synaptojanin 1 (SYNJ1)
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别名
- Synaptojanin 1
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背景
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Synonyms: mouse anti-Synaptojanin 1 Antibody, Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1
Background: Synaptojanin 1 Monoclonal Antibody detects Synaptojanin 1, which is a phosphatidylinositol phosphatase involved in clathrin-mediated endocytosis of synaptic vesicles. Synaptojanin 1 has two alternatively spliced isoforms, one that is ~ 145 kDA and is exclusively expressed in neurons, and the other ~ 170 kDa which is expressed in non-neuronal, peripheral tissues. The gene which encodes Synaptojanin 1, SYNJ1, has been mapped to chromosome 21 thus making it a candidate for involvement in Down's syndrome (DS). It has recently been demonstrated that Ts65Dn mice (the most commonly used model of DS) have altered phosphatidylinositol-4,5-bisphosphate metabolism. This defect is rescued by restoring SYNJ1 to disomy in the Ts65Dn mice.
Gene Name: SYNJ1
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基因ID
- 85238
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UniProt
- Q62910
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途径
- Inositol Metabolic Process, Synaptic Vesicle Exocytosis
抗原
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