RPH3A 抗体 (pSer234)
Quick Overview for RPH3A 抗体 (pSer234) (ABIN6658252)
抗原
See all RPH3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer234
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Supplier Product No.
- 612-401-e22
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Supplier
- Rockland
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原理
- Rabphilin 3A Phospho S234 Antibody
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交叉反应 (详细)
- Rabphilin 3A pS234 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.
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纯化方法
- Anti-Rabphilin 3A pS234 antibody is directed against rat rabphilin 3A protein phosphorylated at serine 234.
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免疫原
- Anti-Rabphilin 3A pS234 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 conjugated to KLH.
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亚型
- IgG
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应用备注
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Immunohistochemistry_Dilution: 1:400
Western_Blot_Dilution: 1:1000
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说明
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Anti-Rabphilin 3A pS234 (Rabbit) antibody is tested for use in Western Blotting and ICC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 82 kDa in size corresponding to rabphilin 3A protein phosphorylated at Ser234 in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- RPH3A (Rabphilin 3A (RPH3A))
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别名
- Rabphilin 3A
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背景
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Synonyms: Rabphilin 3A Homolog, Rabphilin-3A, RP3A, Rph3A, Exophilin 1, Exophilin-1
Background: Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes. The expression of rabphilin 3A is reduced in an animal model of Huntington's disease. Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner. Anti-Rabphilin 3A antibody is ideal for investigators involved in Signal Transduction, Cell Signaling, and Neuroscience research.
Gene Name: RPH3A
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基因ID
- 171039
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UniProt
- P47709
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途径
- Synaptic Vesicle Exocytosis
抗原
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