RPH3A 抗体 (C-Term)
Quick Overview for RPH3A 抗体 (C-Term) (ABIN6658251)
抗原
See all RPH3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 612-401-e21
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Supplier
- Rockland
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原理
- Rabphilin 3A Antibody
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交叉反应 (详细)
- Anti-Rabphilin 3A antibody is directed against rat rabphilin 3A proteins.
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纯化方法
- Anti-Rabphilin 3A antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-Rabphilin 3A Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
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亚型
- IgG
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-Rabphilin 3A (Rabbit) antibody is tested for use in ELISA and in western blotting. Expect a band of approximately 82 kDa in size corresponding to rabphilin 3A protein in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- RPH3A (Rabphilin 3A (RPH3A))
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别名
- Rabphilin 3A
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背景
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Synonyms: Rabphilin 3A Homolog, Rabphilin-3A, RP3A, Rph3A, Exophilin 1, Exophilin-1
Background: Rabphilin 3A antibody detects Rab 3A which is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes. The expression of rabphilin 3A is reduced in an animal model of Huntington's disease. Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner. Anti-Rabphilin 3A antibody is ideal for investigators involved in Signal Transduction, Cell Signaling, and Neuroscience research.
Gene Name: RPH3A
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基因ID
- 171039
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UniProt
- P47709
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途径
- Synaptic Vesicle Exocytosis
抗原
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