STXBP2 抗体 (pSer515)
Quick Overview for STXBP2 抗体 (pSer515) (ABIN6658248)
抗原
See all STXBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer515
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Supplier Product No.
- 600-401-x16
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Supplier
- Rockland
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原理
- Munc18 Phospho S515 Antibody
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交叉反应 (详细)
- Anti-Phospho-Ser515 Munc18 Antibody is directed against Munc18 protein phosphorylated at S515.
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纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
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过滤
- Sterile filtered
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免疫原
- Anti-Phospho-Ser515 Munc18 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser515 of rat Munc18 conjugated to KLH.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
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说明
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Anti-Phospho-Ser515 Munc18 Antibody is tested for Western Blot, and it is specific for the ~65 kDa Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
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有效期
- 12 months
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- STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
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别名
- Stxbp2
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背景
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Synonyms: Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc18-2, Protein unc-18 homolog B, Unc-18B
Background: Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin. Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex. The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein. Munc-18 pS515 Antibody is ideal for researchers interested in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: STXBP2
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基因ID
- 81804
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NCBI登录号
- NP_112388
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UniProt
- Q62753
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
抗原
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