STXBP2 抗体 (pSer515)
-
- 抗原 See all STXBP2 抗体
- STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
-
抗原表位
- pSer515
-
适用
- 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This STXBP2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- Supplier Product No.
- 600-401-x16
- Supplier
- Rockland
- 原理
- Munc18 Phospho S515 Antibody
- 交叉反应 (详细)
- Anti-Phospho-Ser515 Munc18 Antibody is directed against Munc18 protein phosphorylated at S515.
- 纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
- 过滤
- Sterile filtered
- 免疫原
- Anti-Phospho-Ser515 Munc18 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser515 of rat Munc18 conjugated to KLH.
- 亚型
- IgG
- Top Product
- Discover our top product STXBP2 Primary Antibody
-
-
- 应用备注
-
ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
- 说明
-
Anti-Phospho-Ser515 Munc18 Antibody is tested for Western Blot, and it is specific for the ~65 kDa Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None - 储存液
- Without preservative
- 储存条件
- -20 °C
- 储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
- 有效期
- 12 months
-
- 抗原
- STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
- 别名
- Stxbp2 (STXBP2 产品)
- 背景
-
Synonyms: Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc18-2, Protein unc-18 homolog B, Unc-18B
Background: Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin. Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex. The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein. Munc-18 pS515 Antibody is ideal for researchers interested in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: STXBP2
- 基因ID
- 81804
- NCBI登录号
- NP_112388
- UniProt
- Q62753
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
-