Tyrosine Hydroxylase 抗体 (pSer31)
Quick Overview for Tyrosine Hydroxylase 抗体 (pSer31) (ABIN6658241)
抗原
See all Tyrosine Hydroxylase (TH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer31
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Supplier Product No.
- 600-401-e51
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Supplier
- Rockland
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原理
- Tyrosine Hydroxylase phospho S31 Antibody
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交叉反应 (详细)
- Anti-Tyrosine Hydroxylase pS31 Antibody is directed against phosphorylated rat Tyrosine Hydroxylase protein.
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纯化方法
- Tyrosine Hydroxylase pS31 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-Tyrosine Hydroxylase pS31 Antibody was produced repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser31.
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亚型
- IgG
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应用备注
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Immunohistochemistry_Dilution: 1:1000
IF_Microscopy_Dilution: 1:1000
Western_Blot_Dilution: 1:1000
Other: User Optimized
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说明
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Anti-Tyrosine Hydroxylase pS31 (Rabbit) antibody is tested for use in Western Blotting, IHC and ICC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 60 kDa in size corresponding to tyrosine hydroxylase protein phosphorylated at Ser31 in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- Tyrosine Hydroxylase (TH)
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别名
- Tyrosine Hydroxylase
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背景
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Synonyms: Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH
Background: Tyrosine Hydroxylase pS31 Antibody detects phosphorylated Tyrosine Hydroxylase protein. Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.
Gene Name: TH
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基因ID
- 25085
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UniProt
- P04177
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途径
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
抗原
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