GABRB1 抗体 (Cytoplasmic Loop)
Quick Overview for GABRB1 抗体 (Cytoplasmic Loop) (ABIN6658240)
抗原
See all GABRB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cytoplasmic Loop
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Supplier Product No.
- 612-401-d49
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Supplier
- Rockland
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原理
- GABA(A) Receptor beta 1 Antibody
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交叉反应 （详细）
- Anti-GABA(A) Receptor beta 1 Antibody is directed against rat GABA(A) Receptor beta 1.
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纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-GABA(A) Receptor beta 1 Antibody was produced by repeated immunizations with recombinant fusion proteins from the cytoplasmic loop of the beta 1 subunit of rat GABAA.
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亚型
- IgG
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anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (AA 342-430) antibody
GABRB1 适用: 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (AA 1-226) antibodyGABRB1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (C-Term), (pSer434) antibodyGABRB1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (pSer434) antibodyGABRB1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (pSer434) antibodyGABRB1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (AA 401-450) antibodyGABRB1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (AA 214-263) antibodyGABRB1 适用: 人, 小鼠, 大鼠, Cow, 猴, 马, 兔, 犬, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (AA 107-156) antibodyGABRB1 适用: 人, 小鼠, 大鼠, Cow, 猴, 马, 兔, Pig, 豚鼠, 斑马鱼, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) antibodyGABRB1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1) (Cytoplasmic Loop) antibodyGABRB1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-GABA(A) Receptor beta 1 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to the beta 1 subunit of the GABA(A) receptor in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))
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别名
- GABA(A) Receptor beta 1
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背景
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Synonyms: Gamma-aminobutyric acid receptor subunit beta-1, GABA(A) receptor subunit beta-1, GABA(A) receptor subunit ß-1,
Background: Anti-GABA(A) Receptor beta 1 Antibody detects GABA(A) Receptor beta 1. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma- subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor. GABA(A) receptor beta 1 antibody is ideal for investigators involved in Neuroscience.
Gene Name: GABRB1
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基因ID
- 25450
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UniProt
- P15431
抗原
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