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GABBR1 抗体 (pSer923)

This anti-GABBR1 antibody is a 兔 多克隆 antibody detecting GABBR1 in WB. Suitable for 大鼠. This Primary Antibody has been cited in 1 publication.
Rockland
产品编号 ABIN6658230
Supplier Product No.: 612-401-d54
发货至: 中国

Quick Overview for GABBR1 抗体 (pSer923) (ABIN6658230)

抗原

See all GABBR1 抗体
GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This GABBR1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pSer923

    Supplier Product No.

    612-401-d54

    Supplier

    Rockland

    原理

    GABA(B) Receptor 1 phospho S923 Antibody

    交叉反应 (详细)

    Anti-GABA(B) Receptor 1 pS923 Antibody is directed against rat phosphorylated GABA(B) Receptor .

    纯化方法

    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

    免疫原

    Anti-GABA(B) Receptor 1 pS923 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 923 of rat GABA B R1.

    亚型

    IgG
  • 应用备注

    Optional[Neutralization_Dilution]: 1:1000

    说明

    Anti-GABA(B) Receptor 1 pS923 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to GABA(B) receptor 1 protein phosphorylated at Ser923 in the appropriate cell lysate or extract.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

    有效期

    12 months
  • Feng, Gao, Yue, Liu, Zhou, Ren, Teng: "Autophagy-lysosome dysfunction is involved in gastric ischemia-reperfusion injury by promoting microglial activation in the paraventricular nucleus." in: Journal of biochemical and molecular toxicology, Vol. 36, Issue 2, pp. e22957, (2022) (PubMed).

  • 抗原

    GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

    别名

    GABA(B) Receptor 1

    背景

    Synonyms: Gamma-aminobutyric acid type B receptor subunit 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1

    Background: GABA(A) Receptor 1 pS923 Antibody detects phosphorylated GABA(A) Receptor gamma 2. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling. Phosphorylation of Ser 923 is thought to be important in the regulation of GABAB receptor function. GABA(B) Receptor 1 pS923 antibody is ideal for investigators involved in Neuroscience.

    Gene Name: GABBR1

    基因ID

    81657, 8393403

    UniProt

    Q9Z0U4

    途径

    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process
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