GABRA1 抗体 (N-Term)
Quick Overview for GABRA1 抗体 (N-Term) (ABIN6658221)
抗原
See all GABRA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-d43
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Supplier
- Rockland
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原理
- GABA(A) Receptor alpha 1 Antibody
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交叉反应 （详细）
- Labeling is absent in α1-subunit knockout animals.
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纯化方法
- GABA(A) receptor alpha 1 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-GABA(A) Receptor alpha 1 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region of rat GABAA RA1 conjugated to KLH.
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亚型
- IgG
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anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody
GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibodyGABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody (HRP)GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) HRP
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibody (HRP)GABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 HRP
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody (FITC)GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) FITC
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibody (FITC)GABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 FITC
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody (Biotin)GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) Biotin
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibody (Biotin)GABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 Biotin
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody (PE)GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) PE
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibody (PE)GABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 PE
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-GABA(A) Receptor alpha 1 (Rabbit) Antibody is tested for use in Western Blot and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 51 kDa in size corresponding to the alpha 1 subunit of the GABA(A) receptor in rat brain.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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别名
- GABA(A) Receptor alpha 1
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背景
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Synonyms: Gamma-aminobutyric acid receptor subunit alpha-1, GABA(A) receptor subunit alpha-1
Background: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six αs, four βs and four γs, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for α- and β-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a γ-subunit is required for benzo-diazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor. GABA(A) receptor alpha 1 antibody is ideal for investigators involved in Neuroscience.
Gene Name: GABRA1
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基因ID
- 29705
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UniProt
- P62813
抗原
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