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GRIN2C 抗体 (pSer1244)

GRIN2C 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN6658214
Supplier Product No.: 600-401-d96
发货至: 中国
  • 抗原 See all GRIN2C 抗体
    GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
    抗原表位
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1244
    适用
    • 33
    • 20
    • 19
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    大鼠
    宿主
    • 46
    • 5
    克隆类型
    • 48
    • 3
    多克隆
    标记
    • 36
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRIN2C antibody is un-conjugated
    应用范围
    • 37
    • 14
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Supplier Product No.
    600-401-d96
    Supplier
    Rockland
    原理
    NMDA R2C phospho S1244 Antibody
    交叉反应 (详细)
    Anti-NMDA R2C pS1244 antibody is directed against NMDA R2C protein.
    纯化方法
    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification and is specific for the phosphorylated NMDA R2C protein.
    免疫原
    Anti-NMDA R2C pS1244 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244.
    亚型
    IgG
    Top Product
    Discover our top product GRIN2C Primary Antibody
  • 应用备注

    Western_Blot_Dilution: 1:1000

    Other: User Optimized

    说明

    Anti-NMDA R2C pS1244 Antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 140 kDa in size corresponding to the NMDA receptor phosphorylated at Ser1244 in the appropriate cell lysate or extract.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
    别名
    NMDA R2C (GRIN2C 产品)
    背景

    Synonyms: Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C

    Background: NMDA R2C pS1244 Antibody detects phophorylated NMDA R2C protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR2C subunit of the receptor is thought to influence the NMDAR conductance level. Phosphorylation of Ser1244 has been shown to regulate NMDA receptor channel function. Anti-NMDA R2C pS1244 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.

    Gene Name: GRIN2C

    基因ID
    24411
    UniProt
    Q00961
    途径
    Synaptic Membrane
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