GRIN2C 抗体 (pSer1244)
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- 抗原 See all GRIN2C 抗体
- GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
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抗原表位
- pSer1244
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRIN2C antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- Supplier Product No.
- 600-401-d96
- Supplier
- Rockland
- 原理
- NMDA R2C phospho S1244 Antibody
- 交叉反应 (详细)
- Anti-NMDA R2C pS1244 antibody is directed against NMDA R2C protein.
- 纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification and is specific for the phosphorylated NMDA R2C protein.
- 免疫原
- Anti-NMDA R2C pS1244 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244.
- 亚型
- IgG
- Top Product
- Discover our top product GRIN2C Primary Antibody
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- 应用备注
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Western_Blot_Dilution: 1:1000
Other: User Optimized
- 说明
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Anti-NMDA R2C pS1244 Antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 140 kDa in size corresponding to the NMDA receptor phosphorylated at Ser1244 in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
- 别名
- NMDA R2C (GRIN2C 产品)
- 背景
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Synonyms: Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C
Background: NMDA R2C pS1244 Antibody detects phophorylated NMDA R2C protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR2C subunit of the receptor is thought to influence the NMDAR conductance level. Phosphorylation of Ser1244 has been shown to regulate NMDA receptor channel function. Anti-NMDA R2C pS1244 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.
Gene Name: GRIN2C
- 基因ID
- 24411
- UniProt
- Q00961
- 途径
- Synaptic Membrane
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