GRIN2C 抗体 (pSer1244)
Quick Overview for GRIN2C 抗体 (pSer1244) (ABIN6658214)
抗原
See all GRIN2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1244
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Supplier Product No.
- 600-401-d96
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Supplier
- Rockland
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原理
- NMDA R2C phospho S1244 Antibody
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交叉反应 （详细）
- Anti-NMDA R2C pS1244 antibody is directed against NMDA R2C protein.
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纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification and is specific for the phosphorylated NMDA R2C protein.
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免疫原
- Anti-NMDA R2C pS1244 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244.
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (N-Term) antibody
GRIN2C 适用: 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 908-1007) antibodyGRIN2C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) antibodyGRIN2C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 69-118) antibodyGRIN2C 适用: 人, 小鼠, 大鼠, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 1-171) antibodyGRIN2C 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (Internal Region) antibodyGRIN2C 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 365-377), (Extracellular) antibodyGRIN2C 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (pSer1244) antibodyGRIN2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 灵长类 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 1-171) antibodyGRIN2C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (pSer1096) antibodyGRIN2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 灵长类 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western_Blot_Dilution: 1:1000
Other: User Optimized
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说明
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Anti-NMDA R2C pS1244 Antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 140 kDa in size corresponding to the NMDA receptor phosphorylated at Ser1244 in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
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别名
- NMDA R2C
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背景
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Synonyms: Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C
Background: NMDA R2C pS1244 Antibody detects phophorylated NMDA R2C protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR2C subunit of the receptor is thought to influence the NMDAR conductance level. Phosphorylation of Ser1244 has been shown to regulate NMDA receptor channel function. Anti-NMDA R2C pS1244 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.
Gene Name: GRIN2C
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基因ID
- 24411
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UniProt
- Q00961
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途径
- Synaptic Membrane
抗原
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