KCNK3 抗体 (AA 251-411)
Quick Overview for KCNK3 抗体 (AA 251-411) (ABIN6658182)
抗原
See all KCNK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 251-411
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Supplier Product No.
- 200-301-w85
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Supplier
- Rockland
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原理
- TASK1 Potassium Channel Antibody
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交叉反应 (详细)
- BLAST analysis suggests that it is 96 % identical to mouse, 76 % identical to human, and <30 % identical to TASK3.
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纯化方法
- Anti-TASK1 Potassium Channel Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- Anti-TASK1 Potassium Channel Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 251-411 of rat TASK1.
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亚型
- IgG2b
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
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说明
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Anti-TASK1 Potassium Channel Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~50kDa on specific lysates or tissues. Does not cross react with TASK3. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))
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别名
- Kcnk3
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背景
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Synonyms: Potassium channel subfamily K member 3, KCNK3, Acid sensitive potassium channel protein TASK 1, Cardiac two pore background K(+) channel, cTBAK 1, K2p3.1, KCNK9, OAT1, potassium channel subfamily K member 3, rTASK, TASK 1, TBAK1
Background: K+ channels are divided into three subclasses reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions and include TWIK, TREK, TRAAK and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54 % identity with TASK-1, but less than 30 % identity with TASK-2 and other tandem pore K+ channels. Anti-TASK1 Potassium Channel Antibody is ideal for research in Neuroscience, particularly studies concerning the dopaminergic neuron and melatonin signaling.
Gene Name: TASK1
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基因ID
- 29553
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NCBI登录号
- NP_203694
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UniProt
- O54912
抗原
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