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Neuroligin 1 抗体 (AA 718-843) (FITC)

This anti-Neuroligin 1 antibody is a 小鼠 单克隆 antibody detecting Neuroligin 1 in WB, IHC 和 ELISA. Suitable for 大鼠.
Rockland
产品编号 ABIN6658176
Supplier Product No.: 200-302-w75
发货至: 中国

Quick Overview for Neuroligin 1 抗体 (AA 718-843) (FITC) (ABIN6658176)

抗原

See all Neuroligin 1 (NLGN1) 抗体
Neuroligin 1 (NLGN1)

适用

  • 42
  • 40
  • 23
大鼠

宿主

  • 36
  • 29
  • 1
小鼠

克隆类型

  • 40
  • 26
单克隆

标记

  • 22
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neuroligin 1 antibody is conjugated to FITC

应用范围

  • 50
  • 26
  • 22
  • 16
  • 14
  • 13
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

S97A-31
  • 抗原表位

    • 22
    • 16
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 718-843

    Supplier Product No.

    200-302-w75

    Supplier

    Rockland

    原理

    Neuroligin 1 Antibody Fluorescein

    交叉反应 (详细)

    BLAST analysis suggests that it is 99 % identical to mouse, 99 % identical to human and >50 % identical to Neuroligin-2 and -3.

    纯化方法

    Anti-Neuroligin 1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

    过滤

    Sterile filtered

    免疫原

    Anti-Neuroligin 1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 718-843 of rat Neuroligin-1.

    亚型

    IgG1
  • 应用备注

    ELISA_Dilution: 1:5,000

    Immunohistochemistry_Dilution: User Optimized

    Western_Blot_Dilution: 1:500

    说明

    Anti-Neuroligin 1 FITC Conjugated Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~120kDa on specific lysates or tissues. Does not cross react with other Neuroligins. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.1 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    Neuroligin 1 (NLGN1)

    别名

    Neuroligin 1

    背景

    Synonyms: NLG 1, KIAA1070, MGC45115, Neuroligin-1, NL1, NLG1, Nlgn1

    Background: Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord. Anti-Neuroligin-1 is ideal for research in Neuroscience, including narcolepsy and synaptic neurotransmission: GABAergic inhibition, as well as Cell Adhesion.

    Gene Name: Neuroligin-1

    基因ID

    116647

    UniProt

    Q62765

    途径

    Synaptic Membrane, Synaptic Vesicle Exocytosis
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