Metabotropic Glutamate Receptor 1 抗体 (C-Term)
Quick Overview for Metabotropic Glutamate Receptor 1 抗体 (C-Term) (ABIN6658163)
抗原
See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 600-401-d75
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Supplier
- Rockland
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原理
- mGluR1a Antibody
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纯化方法
- Anti-mGluR1a antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling blocked by preadsorption of antibody with the peptide used to generate the antibody.
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免疫原
- Anti-mGluR1a Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
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亚型
- IgG
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anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 165-592) antibody
GRM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 501-516), (Extracellular) antibodyGRM1 适用: 大鼠 WB, IP, IF, IC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) antibodyGRM1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5E12D8 unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 880-1017) antibodyGRM1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (C-Term) antibodyGRM1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (N-Term) antibodyGRM1 适用: 人, Cow, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (Internal Region) antibodyGRM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:500
Western_Blot_Dilution: 1:1000
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说明
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Anti-mGluR1a antibody is tested for use in Western Blotting and IHC. Expect a band of approximately 125 kDa monomer and 250 kDa mGluR1a dimer in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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别名
- mGluR1a
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背景
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Synonyms: mGluR1, Metabotropic Glutamate Receptor 1a
Background: mGluR1a antibodies detect GluR1a. GluR1a is the metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast, activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase. The mGluR1 receptor may also be critically involved in limiting the deleterious effects of excitotoxicity. Therefore, mGluR1a antibody is ideal for investigators involved in neuronal plasticitiy, cell signaling and neuroscience.
Gene Name: GRM1
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基因ID
- 24414
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UniProt
- P23385
抗原
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