GRM7 抗体 (pSer862)
Quick Overview for GRM7 抗体 (pSer862) (ABIN6658162)
抗原
See all GRM7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer862
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Supplier Product No.
- 600-401-d78
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Supplier
- Rockland
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原理
- mGluR7 phospho S862 Antibody
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交叉反应 （详细）
- Anti mGluR7 pS862 antibody is directed against mGluR7 phosphorylated at Ser862.
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纯化方法
- GluR7 antibody is affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-mGluR7 pS862 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 862 conjugated to KLH.
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亚型
- IgG
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anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 454-590) antibody
GRM7 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G8D3 unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 454-590) antibodyGRM7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G8A2 unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (Extracellular Domain) antibodyGRM7 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 猴, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 猴, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 377-390), (Extracellular) antibodyGRM7 适用: 大鼠 WB, IHC, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 适用: 人, Cow WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-mGluR7 pS862 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to the mGluR7 protein phosphorylated at Ser862 in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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别名
- mGluR7
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背景
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Synonyms: mGluR7, Metabotropic Glutamate Receptor 7
Background: mGluR7 pS862 antibodiy detects mGluR7 when phosphorylated at Ser862. Metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. The mGluRs are divided into three groups based on sequence identity and pharmacological properties: group I (mGluR1 and mGluR5) are localized in the perisynaptic region of the postsynaptic membrane, whereas group II (mGlur2 and mGluR3) and group III (mGluR4,6,7 and 8) are localized predominantly at presynaptic terminals. PKC phosphorylation of serine 862 on mGluR7 has been shown to be critical for stabilizing receptor surface expression and promoting binding to the synaptic PDZ-domain-containing protein PICK1. Therefore, mGluR7 pS862 antibody is ideal for investigators involved in neuronal circuitry and more generally in Neuroscience.
Gene Name: GRM7
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基因ID
- 81672
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UniProt
- P35400
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途径
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
抗原
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