SLC6A1 抗体 (C-Term)
Quick Overview for SLC6A1 抗体 (C-Term) (ABIN6658161)
抗原
See all SLC6A1 (GAT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 612-401-d56
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Supplier
- Rockland
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原理
- GABA Transporter 1 (GAT1) Antibody
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交叉反应 (详细)
- Anti-GABA Transporter 1 antibody is directed against rat GABA Transporter 1.
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纯化方法
- GABA Transporter 1 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-GABA Transporter 1 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
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亚型
- IgG
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应用备注
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Immunohistochemistry_Dilution: 1:100-200
Western_Blot_Dilution: 1:1000
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说明
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Anti-GAT1 (Rabbit) Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 67 kDa in size corresponding to GABA Transporter 1 protein in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))
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背景
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Synonyms: Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1
Background: Gamma-aminobutyric acid (GABA) Antibody detects GABA which is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia. GAT-1 is thought to play a key role in epileptogenesis. Anti-GAT1 Antibody is ideal for investigators involved in Neuroscience.
Gene Name: SLC6A1
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基因ID
- 79212
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UniProt
- P23978
抗原
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