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SLC6A1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects SLC6A1 in WB 和 IHC. It exhibits reactivity toward 大鼠.
Rockland
产品编号 ABIN6658161
Supplier Product No.: 612-401-d56
发货至: 中国
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Quick Overview for SLC6A1 抗体 (C-Term) (ABIN6658161)

抗原

See all SLC6A1 (GAT1) 抗体
SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This SLC6A1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    Supplier Product No.

    612-401-d56

    Supplier

    Rockland

    原理

    GABA Transporter 1 (GAT1) Antibody

    交叉反应 (详细)

    Anti-GABA Transporter 1 antibody is directed against rat GABA Transporter 1.

    纯化方法

    GABA Transporter 1 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.

    免疫原

    Anti-GABA Transporter 1 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry_Dilution: 1:100-200

    Western_Blot_Dilution: 1:1000

    说明

    Anti-GAT1 (Rabbit) Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 67 kDa in size corresponding to GABA Transporter 1 protein in the appropriate cell lysate or extract.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

    背景

    Synonyms: Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1

    Background: Gamma-aminobutyric acid (GABA) Antibody detects GABA which is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia. GAT-1 is thought to play a key role in epileptogenesis. Anti-GAT1 Antibody is ideal for investigators involved in Neuroscience.

    Gene Name: SLC6A1

    基因ID

    79212

    UniProt

    P23978
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