GAP43 抗体 (pSer41)
Quick Overview for GAP43 抗体 (pSer41) (ABIN6658158)
抗原
See all GAP43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer41
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Supplier Product No.
- 612-401-d59
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Supplier
- Rockland
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原理
- Neuromodulin phospho S41 Antibody
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交叉反应 （详细）
- This antibody is specific for the phosphorylated forms of the protein.
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纯化方法
- Anti-GAP43 pS41 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-Neuromodulin Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser41 of GAP43.
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亚型
- IgG
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anti-Growth Associated Protein 43 (GAP43) (AA 9-100) antibody
GAP43 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-274) antibodyGAP43 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (pSer41) antibodyGAP43 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 8-226) antibodyGAP43 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal Mix unconjugated
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应用备注
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Western_Blot_Dilution: 1:1000
Other: User Optimized
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说明
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Anti-GAP43 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 50 kDa in size corresponding to neuromodulin protein phosphorylated at Ser41 in the appropriate cell lysate or extract. In some tissues, the antibody also recognized a higher molecular weight protein that may be an aggregate or oligomer.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- GAP43 (Growth Associated Protein 43 (GAP43))
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别名
- Neuromodulin (GAP43)
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背景
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Synonyms: Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43, Protein F1, Neural phosphoprotein B-50, pp46
Background: Gap-43 pS41 antibody detects phophorylated GAP43 at position S41. Gap43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that Gap-43 serves to amplify pathfinding signals from the growth cone. Gap-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C modulates the interaction of Gap-43 with actin and may also affect eurotransmitter release during forms of plasticity like LTP. Anti-Gap-43 pS41 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.
Gene Name: GAP43
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基因ID
- 29423
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UniProt
- P07936
抗原
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