GRIN2B 抗体 (pSer1166)
Quick Overview for GRIN2B 抗体 (pSer1166) (ABIN6658155)
抗原
See all GRIN2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1166
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Supplier Product No.
- 600-401-x17
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Supplier
- Rockland
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原理
- NMDA NR2B Subunit Phospho S1166 Antibody
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交叉反应 （详细）
- Anti-Phospho-Ser1166 NMDA Receptor NR2B Subunit Antibody is directed against NMDA protein phosphorylated at S1166.
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纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
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过滤
- Sterile filtered
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免疫原
- Anti-Phospho-Ser1166 NMDA Receptor NR2B Subunit Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1166 of rat NMDA Receptor NR2B Subunit conjugated to KLH.
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 27-163) antibody
GRIN2B 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E9A8 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (HRP)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (FITC)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 FITC
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Biotin)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 Biotin
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PE)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 PE
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (APC)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 APC
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PerCP)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 PerCP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 488)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 488
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 594)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 594
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 390)GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 390
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应用备注
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ELISA_Dilution: 1:2,500
Western_Blot_Dilution: 1:250
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说明
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Anti-Phospho-Ser1166 NMDA Receptor NR2B Subunit Antibody is tested for Western Blots and is specific for the ~180 kDa NMDAR NR2B subunit phosphorylated at Ser1166. Immunolabeling of the NMDA NR2B subunit band is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
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有效期
- 12 months
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- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
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别名
- NMDA NR2B Subunit
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背景
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Synonyms: Glutamate receptor ionotropic, NMDA 2B, GluN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B
Background: The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B-subunit of the NMDA Receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Phosphorylation of Ser1166 is thought to play an essential role in memory and neuronal development. NMDA pS1166 Receptor NR2B Subunit Antibody is ideal for researchers interested in neuroscience research.
Gene Name: GRIN2B
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基因ID
- 24410
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NCBI登录号
- NP_036706
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UniProt
- Q00960
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途径
- Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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