CDK1 抗体 (pTyr15)
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北京 101111
Quick Overview for CDK1 抗体 (pTyr15) (ABIN6658147)
抗原
See all CDK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr15
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Supplier Product No.
- 600-401-160
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Supplier
- Rockland
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原理
- cdc2 phospho Y15 Antibody
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交叉反应 (详细)
- Anti-cdc2 pY15 Antibody is directed against rat cdc2 protein phosphorylated at Y15.
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纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
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免疫原
- Anti-cdc2 pY15 Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues surrounding Tyr 15.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
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说明
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Anti-cdc2 pY15 antibody is tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 34 kDa in size corresponding to cdc2 protein in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
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别名
- cdc2
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背景
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Synonyms: CDC-like kinase 2, Clk2
Background: Cdc2 pY15 antibody recognizes Cdc2 which is a highly conserved protein serine kinase that plays a key role in regulation of the cell cycle. The ability of cdc2 to exercise control over the cell cycle is dependent upon the phosphorylation of Tyr15 in cdc2. Cdc2 expression in brain has been linked to both neurogenesis and apoptosis. Anti-Cdc2 pY15 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: CLK2
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基因ID
- 54237
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NCBI登录号
- NP_062169
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UniProt
- P39951
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
抗原
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