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YWHAB 抗体 (pSer58)

Rockland 600-401-d02 YWHAB 适用: 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN6658145
Supplier Product No.: 600-401-d02
发货至: 中国
  • 抗原 See all YWHAB 抗体
    YWHAB (14-3-3 alpha + beta (YWHAB))
    抗原表位
    • 15
    • 12
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer58
    适用
    • 75
    • 48
    • 47
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 71
    • 7
    • 1
    克隆类型
    • 63
    • 16
    多克隆
    标记
    • 38
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This YWHAB antibody is un-conjugated
    应用范围
    • 56
    • 24
    • 19
    • 14
    • 14
    • 13
    • 13
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Supplier Product No.
    600-401-d02
    Supplier
    Rockland
    原理
    14-3-3 phospho S58 Antibody
    交叉反应 (详细)
    Anti-14-3-3 pS58 antibody is directed against rat 14-3-3 protein phosphorylated at S58.
    纯化方法
    The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
    免疫原
    Anti-14-3-3 pS58 antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser58.
    亚型
    IgG
    Top Product
    Discover our top product YWHAB Primary Antibody
  • 应用备注

    ELISA_Dilution: 1:10,000

    Immunohistochemistry_Dilution: 1:500

    Western_Blot_Dilution: 1:1000

    说明

    Anti-14-3-3 pS58 antibody is tested for use in ELISA, Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 29 kDa in size corresponding to the 14-3-3 proteins phosphorylated at Ser58 in the appropriate cell lysate or extract.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    YWHAB (14-3-3 alpha + beta (YWHAB))
    别名
    Ywhab (YWHAB 产品)
    背景

    Synonyms: 14-3-3 protein beta/alpha, Prepronerve growth factor RNH-1, Protein kinase C inhibitor protein 1

    Background: 14-3-3 pS58 antibody detects 14-3-3 protein phosphorylated at S58. 14-3-3 is a member of a family of highly conserved proteins that appear to have multiple roles in cell signaling. 14-3-3 is abundantly expressed in the brain and has been detected in the cerebrospinal fluid of patients with different neurological disorders. 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms. 14-3-3 affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking. These functions are facilitated by, if not dependent on, its dimeric structure. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation. Anti-14-3-3 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

    Gene Name: YWHAB

    基因ID
    56011
    NCBI登录号
    NP_062250
    UniProt
    P35213
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location
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