GRIN2C 抗体 (N-Term)
(1 reference)
Quick Overview for GRIN2C 抗体 (N-Term) (ABIN6658125)
抗原
See all GRIN2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-d94
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Supplier
- Rockland
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原理
- NMDA R2C Antibody
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交叉反应 （详细）
- Anti-NMDA R2C antibody is directed against NMDA R2C protein.
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纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-NMDA R2C Antibody was produced by repeated immunizations with a fusion proteins from the N-terminal region of the NR2C subunit.
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (N-Term) antibody
GRIN2C 适用: 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 908-1007) antibodyGRIN2C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) antibodyGRIN2C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 69-118) antibodyGRIN2C 适用: 人, 小鼠, 大鼠, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 1-171) antibodyGRIN2C 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (Internal Region) antibodyGRIN2C 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 365-377), (Extracellular) antibodyGRIN2C 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (pSer1244) antibodyGRIN2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 灵长类 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 1-171) antibodyGRIN2C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (pSer1096) antibodyGRIN2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 灵长类 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunoprecipitation_Dilution: 3 μL per 200 μg lysate
Immunohistochemistry_Dilution: 1:1000-2000
IF_Microscopy_Dilution: 1:1000-2000
Western_Blot_Dilution: 1:1000
Other: User Optimized
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说明
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Anti-NMDA R2C Antibody is tested for use in Western Blotting and Immunoprecipitation and suitable for IHC and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 140 kDa in size corresponding to the NR2C subunit of the NMDA receptor. This antibody also labels the approximately 180 kDa NR2A and NR2B subunits of the NMDA receptor.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Neutral PBS
Reconstitution_Volume: 50μL
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Free d-Amino Acids in Salivary Gland in Rat." in: Biology, Vol. 11, Issue 3, (2022) (PubMed).
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: "Free d-Amino Acids in Salivary Gland in Rat." in: Biology, Vol. 11, Issue 3, (2022) (PubMed).
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- GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
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别名
- NMDA R2C
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背景
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Synonyms: Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C
Background: NMDA R2C Antibody detects NMDA R2C protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. The NR2C subunit of the receptor is thought to influence the NMDAR conductance level. Anti-NMDA R2C Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.
Gene Name: GRIN2C
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基因ID
- 24411
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UniProt
- Q00961
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途径
- Synaptic Membrane
抗原
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