CDK5 抗体
(4 references)
Quick Overview for CDK5 抗体 (ABIN6658103)
抗原
See all CDK5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
Supplier Product No.
- 200-301-163
-
Supplier
- Rockland
-
原理
- Cdk5 Antibody
-
交叉反应 （详细）
- Anti-CDK5 Antibody is directed against rat CDK5 protein.
-
纯化方法
- The antibody was Protein G purified from cell culture supernatant by chromatography.
-
免疫原
- Anti-CDK5 Antibody was produced by repeated immunizations with purified rat Cdk5
-
亚型
- IgG1
-
-
anti-Cyclin-Dependent Kinase 5 (CDK5) antibody
CDK5 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibodyCDK5 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 15-100) antibodyCDK5 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibodyCDK5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) antibodyCDK5 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1552CT262-105-8 unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibodyCDK5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 254-289) antibodyCDK5 适用: 人, 小鼠 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) (Tyr15) antibodyCDK5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 254-289), (C-Term) antibodyCDK5 适用: 人, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB50850 unconjugated
anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibodyCDK5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry_Dilution: 1:500
Western_Blot_Dilution: 1:1000
-
说明
-
Suggested Applications: IF
Anti-CDK5 (Mouse) has been tested for use in Western Blotting and is excellent for use in IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of ~28kDa in size in rat striatal lysates by Western Blotting. Anti-CDK5 antibodies also work well for immunocytochemistry using primary cultured rat neurons and for immunohistochemistry on mouse brain tissue. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
-
: "Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma." in: bioRxiv : the preprint server for biology, (2023) (PubMed).
: "Integrated regulation of PKA by fast and slow neurotransmission in the nucleus accumbens controls plasticity and stress responses." in: The Journal of biological chemistry, Vol. 298, Issue 8, pp. 102245, (2022) (PubMed).
: "Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer." in: Cell reports, Vol. 40, Issue 7, pp. 111218, (2022) (PubMed).
: "Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors." in: Oncogenesis, Vol. 10, Issue 12, pp. 83, (2021) (PubMed).
-
: "Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma." in: bioRxiv : the preprint server for biology, (2023) (PubMed).
-
- CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
-
别名
- CDK5
-
背景
-
Synonyms: mouse anti-cdk5 antibody, cdk, mouse anti-Cyclin-dependent kinase 5, Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit
Background: CDK5 antibody recognizes the neuronal protein kinase Cdk5 which is implicated in a vast array of normal neuronal functions including regulation of neurotransmitter synthesis, the presynaptic vesicle cycle, neurotransmitter receptor trafficking and dopamine neurotransmission. At the same time Cdk5 has been implicated in a plethora of neurological and neuropsychiatric disorders including Alzheimer's, Parkinson's, Huntington's, epilepsy, schizophrenia, and drug addiction. Detection of Cdk5 in normal samples as well as tissue undergoing neurodegeneration may advance studies in these areas. Moreover, this antibody may allow more accurate postmortem evaluations of Cdk5 protein expression, and thus serve as a valuable new reagent for neuropathology. Anti-CDK5 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: CDK5
-
基因ID
- 140908
-
UniProt
- Q03114
-
途径
- Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
抗原
-
