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CNTNAP1 抗体

This anti-CNTNAP1 antibody is a 小鼠 单克隆 antibody detecting CNTNAP1 in WB, IHC, IP 和 FM. Suitable for 大鼠.
Rockland
产品编号 ABIN6658098
Supplier Product No.: 200-301-f03
发货至: 中国

Quick Overview for CNTNAP1 抗体 (ABIN6658098)

抗原

See all CNTNAP1 抗体
CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

适用

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大鼠

宿主

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  • 2
小鼠

克隆类型

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  • 12
单克隆

标记

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This CNTNAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

克隆位点

S65-35
  • Supplier Product No.

    200-301-f03

    Supplier

    Rockland

    原理

    Caspr Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with CASPR from Mouse, Human, and Rat based on 100 % homology with the immunizing sequence.

    纯化方法

    Anti-CASPR Antibody was purified by Protein G chromatography.

    过滤

    Sterile filtered

    免疫原

    CASPR Antibody was produced in mice by repeated immunizations with a fusion protein of rat CASPR.

    亚型

    IgG1
  • 应用备注

    Immunoprecipitation_Dilution: User Optimized

    Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

    IF_Microscopy_Dilution: 1.0-10 μg/mL

    Western_Blot_Dilution: 1 μg/mL

    说明

    Anti-CASPR Antibody is tested by WB, IP, and IHC. Expect a band approximately ~220kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

    别名

    CASPR

    背景

    Synonyms: CASPR1, CNTP1, Contactin associated protein 1, NCP1, Paranodin, Neurexin 4, p190, CASPR, NRXN4

    Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex. Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.

    Gene Name: CNTNAP1

    基因ID

    84008

    NCBI登录号

    NP_114450

    UniProt

    P97846

    途径

    Cell-Cell Junction Organization
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