Neuroligin 3 抗体 (AA 730-848) (Biotin)
Quick Overview for Neuroligin 3 抗体 (AA 730-848) (Biotin) (ABIN6658085)
抗原
See all Neuroligin 3 (NLGN3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 730-848
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Supplier Product No.
- 200-306-w83
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Supplier
- Rockland
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原理
- Neuroligin 3 Antibody Biotin
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交叉反应 (详细)
- BLAST analysis suggests that it is 99 % identical to mouse, 98 % identical to human, ~60 % identical with Neuroligin-1 and ~40 % identical to Neuroligin-2.
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纯化方法
- Anti-Neuroligin-3 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- Anti-Neuroligin 3 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 730-848 of rat Neuroligin-3.
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亚型
- IgG1
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应用备注
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ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: User Optimized
Western_Blot_Dilution: 1:1000
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说明
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Anti-Neuroligin-3 Biotin Conjugated Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~110kDa on specific lysates or tissues. Does not cross react with Neuroligin -1, -2, or -4. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Neuroligin 3 (NLGN3)
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别名
- Neuroligin 3
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背景
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Synonyms: Gliotactin homolog, Neuroligin-3, Nlgn3, NLGN3_HUMAN
Background: Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. Anti-Neuroligin-3 is ideal for research in Neuroscience, including autism research, and Cell Adhesion and Communication.
Gene Name: Neuroligin-3
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基因ID
- 171297
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UniProt
- Q62889
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途径
- Synaptic Membrane
抗原
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