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GRIA2 抗体 (C-Term)

This anti-GRIA2 antibody is a 小鼠 单克隆 antibody detecting GRIA2 in WB, IHC, IP 和 FM. Suitable for 大鼠.
Rockland
产品编号 ABIN6658073
Supplier Product No.: 200-301-f34
发货至: 中国

Quick Overview for GRIA2 抗体 (C-Term) (ABIN6658073)

抗原

See all GRIA2 抗体
GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

适用

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  • 5
  • 3
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  • 2
  • 1
  • 1
大鼠

宿主

  • 92
  • 25
  • 1
小鼠

克隆类型

  • 80
  • 38
单克隆

标记

  • 68
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
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  • 2
  • 2
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  • 2
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  • 1
  • 1
  • 1
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This GRIA2 antibody is un-conjugated

应用范围

  • 95
  • 45
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  • 7
  • 3
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  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

克隆位点

S21-32
  • 抗原表位

    • 28
    • 16
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Supplier Product No.

    200-301-f34

    Supplier

    Rockland

    原理

    GluR2 Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with GluR2 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

    纯化方法

    Anti-GluR2 Antibody was purified by Protein G chromatography.

    过滤

    Sterile filtered

    免疫原

    GluR2 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to a cytoplasmic C-terminus region of rat GluR2.

    亚型

    IgG1
  • 应用备注

    Immunoprecipitation_Dilution: User Optimized

    Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

    IF_Microscopy_Dilution: 1.0-10 μg/mL

    Western_Blot_Dilution: 1 μg/mL

    说明

    Anti-GluR2 Antibody is tested for use in WB and IHC, and is suitable in IP and Immuno-gold EM. Expect a band approximately ~90kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

    别名

    GluR2

    背景

    Synonyms: Glutamate receptor 2, GluR-2, GLUR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2

    Background: The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers. GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium.

    Gene Name: GRIA2

    基因ID

    29627

    UniProt

    P19491

    途径

    PI3K-Akt Signaling
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