GAP43 抗体 (C-Term)
Quick Overview for GAP43 抗体 (C-Term) (ABIN6658062)
抗原
See all GAP43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 200-901-x10
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Supplier
- Rockland
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原理
- GAP43 Antibody
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纯化方法
- Anti-GAP-43 Antibody is a purified total IgY fraction.
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过滤
- Sterile filtered
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免疫原
- Anti-GAP-43 Antibody was produced in chickens by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GAP43 conjugated to KLH.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:20,000
Immunohistochemistry_Dilution: 1:500-1:2000
Western_Blot_Dilution: 1:2000
Other: ICC: 1:500-1:2000
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说明
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Anti-GAP-43 Antibody is tested for Western Blot, immunohistochemistry, and immunocytochemistry, and it is specific for the ~43k GAP-43 protein. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
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有效期
- 12 months
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- GAP43 (Growth Associated Protein 43 (GAP43))
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别名
- GAP-43
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背景
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Synonyms: Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43, Protein F1
Background: GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone. GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C modulates the interaction of GAP-43 with actin and may also affect neurotransmitter release during forms of plasticity like LTP. GAP-43 Antibody is ideal for researchers interested in neuroscience research.
Gene Name: GAP43
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基因ID
- 29423
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NCBI登录号
- NP_058891
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UniProt
- P07936
抗原
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