5HT1B Receptor 抗体
Quick Overview for 5HT1B Receptor 抗体 (ABIN6658050)
抗原
See all 5HT1B Receptor (HTR1B) 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-401-i11
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Supplier
- Rockland
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原理
- Serotonin Receptor 1B Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 1B from human, mouse and rat based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-Serotonin Receptor 1B Antibody was purified by Protein G chromatography.
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免疫原
- Serotonin Receptor 1B Antibody was produced from whole rabbit serum prepared by repeated immunizations with a mixture of synthetic peptides corresponding to two internal amino acid sequences in rat 5-HT1BR protein.
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亚型
- IgG
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anti-Serotonin Receptor 1B (HTR1B) (Internal Region) antibody
HTR1B 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (Internal Region) antibodyHTR1B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (AA 1-49) antibodyHTR1B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (Cytoplasmic Domain) antibodyHTR1B 适用: 人, 大鼠, 小鼠, 犬, Bat, Cow, 豚鼠, Hamster, 兔, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (C-Term) antibodyVerified HTR1B 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (AA 33-49), (Extracellular) antibodyHTR1B 适用: 人 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (AA 8-26) antibodyHTR1B 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (N-Term) antibodyHTR1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1B (HTR1B) (N-Term) antibodyHTR1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optional[Neutralization_Dilution]: 1-2 μg/mL
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说明
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Anti-Serotonin Receptor 1B antibody is tested for use in WB and suitable in IF/ICC. Expect a band approximately 40kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))
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别名
- Serotonin Receptor 1B
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背景
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Synonyms: 5ht1b
Background: Anti-Serotonin Receptor 1B antibody detects rat Serotonin Receptor 1B. Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. The in situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei. Anti-Serotonin Receptor 1B antibody is ideal for investigators involved in neurobiology.
Gene Name: Htr1b
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基因ID
- 25075
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NCBI登录号
- NP_071561
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UniProt
- P28564
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途径
- JAK/STAT Signaling, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins
抗原
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