NrCAM 抗体 (AA 30-845) (FITC)
Quick Overview for NrCAM 抗体 (AA 30-845) (FITC) (ABIN6658002)
抗原
See all NrCAM (NRCAM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 30-845
-
Supplier Product No.
- 200-302-w74
-
Supplier
- Rockland
-
原理
- NrCAM Antibody Fluorescein
-
交叉反应 （详细）
- BLAST analysis suggests that it is 96 % identical to rat, 91 % identical to human and ~50 % identical to Neurofascin.
-
纯化方法
- Anti-NrCAM Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
-
过滤
- Sterile filtered
-
免疫原
- Anti-NrCAM Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 30-845 of mouse NrCAM.
-
亚型
- IgG2a
-
-
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 1192-1255) antibody
NRCAM 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 7D8C5 unconjugated
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 1194-1299) antibodyNRCAM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 30-845), (Extracellular Domain) antibodyNRCAM 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S364-51 unconjugated
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 30-845), (Extracellular Domain) antibody (HRP)NRCAM 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S364-51 HRP
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 30-845), (Extracellular Domain) antibody (FITC)NRCAM 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S364-51 FITC
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 30-845), (Extracellular Domain) antibody (Biotin)NRCAM 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S364-51 Biotin
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 30-845), (Extracellular Domain) antibody (PE)NRCAM 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S364-51 PE
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 30-845), (Extracellular Domain) antibody (PerCP)NRCAM 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S364-51 PerCP
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 30-845), (Extracellular Domain) antibody (APC)NRCAM 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S364-51 APC
anti-Neuronal Cell Adhesion Molecule (NRCAM) (AA 30-845), (Extracellular Domain) antibody (Atto 488)NRCAM 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S364-51 Atto 488
-
-
应用备注
-
ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
-
说明
-
Anti-NrCAM FITC Conjugated Antibody is suitable for Western Blots and Immunocytochemistry. Expect a band approximately ~160kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))
-
别名
- NrCAM
-
背景
-
Synonyms: Neuronal cell adhesion molecule, Bravo, hBravo, KIAA0343, MGC138845, MGC138846, Neuronal surface protein Bravo, Ng CAM related, Ng-CAM-related, NgCAM related cell adhesion molecule, NgCAM-related cell adhesion molecule, Nr CAM, Nr-CAM
Background: Neuronal cell adhesion molecule (NrCAM) is a cell surface protein of the immunoglobulin (Ig) superfamily. NrCAM (also known as Bravo) contains six Ig domains, five fibronectin repeats, a transmembrane region and an intracellular domain. NrCAM is expressed in brain, spinal cord, peripheral nervous system and pancreas. In the spinal cord, NrCAM acts as a ligand for axonin-1 to guide commissural axons across the floor plate. NrCAM also acts as a ligand for F3 to control actin-dependent growth cone motility. NrCAM interacts with neurofascin and may facilitate the clustering of the cystoskeletal protein ankyrin G and the voltage-dependent sodium channel proteins at the node of Ranvier. NrCAM expression may play a role in the severity of certain types of tumors. NrCAM is overexpressed in high-grade astrocytomas, gliomas and glioblastoma tumor tissues. Anti-NrCam is ideal for research in Cancer and Neuroscience. In the pancreas, NrCAM expression is upregulated in intraductal hyperplasia. Antisense NrCAM reduces the tumorigenic properties of human glioblastoma cells in vitro and slowed tumor growth in vivo. The gene encoding human NrCAM maps to chromosome 7q31.1-q31.2.
Gene Name: NrCAM
-
基因ID
- 319504
-
UniProt
- Q810U4
-
途径
- Regulation of Cell Size
抗原
-
