MFN2 抗体 (AA 370-600) (PerCP)
Quick Overview for MFN2 抗体 (AA 370-600) (PerCP) (ABIN6657984)
抗原
See all MFN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 370-600
-
Supplier Product No.
- 200-365-w71
-
Supplier
- Rockland
-
原理
- Mitofusin 2 Antibody PerCP
-
交叉反应 （详细）
- BLAST analysis suggests that it is 97 % identical to rat, 92 % identical to human and ~55 % identical to Mitofusin 1.
-
纯化方法
- Anti-Mitofusin 2 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
-
过滤
- Sterile filtered
-
免疫原
- Anti-Mitofusin 2 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 370-600 of mouse Mitofusin 2.
-
亚型
- IgG2a
-
-
anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Mitofusin 2 (MFN2) (AA 1-120) antibodyMFN2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 500-600) antibodyMFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 687-757) antibodyMFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 447-476) antibodyMFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (N-Term) antibodyMFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibodyMFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 HRP
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 FITC
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Biotin)MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 Biotin
-
-
应用备注
-
ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: User Optimized
Western_Blot_Dilution: 1:1000
Other: ICC/IF: 1:100
-
说明
-
Anti-Mitofusin 2 PerCP Conjugated Antibody is tested for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~90kDa on specific lysates or tissues. Does not cross react with Mitofusin 1. Specific conditions for reactivity should be optimized by the end user.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- MFN2 (Mitofusin 2 (MFN2))
-
别名
- Mitofusin 2
-
背景
-
Synonyms: CMT2A, CMT2A2, CPRP 1, CPRP1, Fzo, HSG, hyperplasia suppressor gene, Hypertension related protein 1, KIAA0214, MARF, MFN 2, Mfn2, Mitochondrial assembly regulatory factor, Mitofusin-2, Mitofusin2, Transmembrane GTPase MFN2
Background: Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression. Anti-Mitofusin-2 is ideal for research in Metabolic Processes and Hemostasis.
Gene Name: Mitofusin-2
-
基因ID
- 170731
-
NCBI登录号
- NP_001272849
-
UniProt
- Q80U63
-
途径
- Skeletal Muscle Fiber Development
抗原
-
