COX IV 抗体 (pSer58)
Quick Overview for COX IV 抗体 (pSer58) (ABIN6657951)
抗原
See all COX IV (COX4I1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer58
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Supplier Product No.
- 600-401-x00
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Supplier
- Rockland
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原理
- CoxIV phospho S58 Antibody
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纯化方法
- Anti-Phospho-Ser58 COXIV Antibody was prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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过滤
- Sterile filtered
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免疫原
- Anti-Phospho-Ser58 COXIV Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser58 of mouse COXIV protein conjugated to KLH.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
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说明
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Anti-Phospho-Ser58 COXIV Antibody has been tested by Western Blots and is specific for the ~17k COXIV-1 protein phosphorylated at Ser58. Immunolabeling is blocked by the phospho-peptide used as antigen but not by the corresponding dephospho-peptide. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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有效期
- 12 months
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- COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))
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别名
- COXIV
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背景
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Synonyms: Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1
Background: COX, also known as cytochrome c oxidase, has 12 subunits that make up the transmembrane mitochondrial protein. Subunit IV has two isoforms, COXIV-1 and COXIV-2. COXIV-1 is expressed ubiquitously while COXIV-2 is highly expressed in adult lung and low levels in brain and heart. Phosphorylation of amino acid residue ser58 of the COXIV-1 protein is a PKA-dependent regulation of COX and plays an important role in metabolism and CREB cycle activation. COX IV pS58 Antibody is ideal for researchers interested in cell cycle research.
Gene Name: COX4i1
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基因ID
- 12857
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NCBI登录号
- NP_034071
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UniProt
- P19783
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途径
- Proton Transport
抗原
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