PCDHGA1 抗体 (AA 808-931) (PE)
Quick Overview for PCDHGA1 抗体 (AA 808-931) (PE) (ABIN6657949)
抗原
See all PCDHGA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 808-931
-
Supplier Product No.
- 200-308-w68
-
Supplier
- Rockland
-
原理
- Protocadherin Gamma (pan) Antibody Phycoerythrin
-
交叉反应 （详细）
- BLAST analysis suggests that it is 99 % identical to human.
-
纯化方法
- Anti-Protocadherin Gamma (pan) Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
-
过滤
- Sterile filtered
-
免疫原
- Anti-Protocadherin Gamma (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 808-931 of mouse Protocadherin-gamma-A1 that is shared by all 22 Gamma-protocadherins.
-
亚型
- IgG1
-
-
anti-Protocadherin gamma A1 (PCDHGA1) (AA 241-340) antibody
PCDHGA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Protocadherin gamma A1 (PCDHGA1) (AA 287-315) antibodyPCDHGA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31763 unconjugated
anti-Protocadherin gamma A1 (PCDHGA1) (AA 294-323), (Middle Region) antibodyPCDHGA1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
Other: ICC/IF: 1:100
-
说明
-
Anti-Protocadherin Gamma (pan) R-PE Conjugated Antibody is tested for Western Blots and Immunocytochemistry. Expect a band approximately ~100 kDa on specific lysates or tissues. It will cross react with all Gamma-protocadherins -A, -B, and -C. Specific conditions for reactivity should be optimized by the end user.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
-
有效期
- 12 months
-
-
- PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))
-
别名
- Pcdhga1
-
背景
-
Synonyms: PCDH, Protocadherin Gamma antibody, PCDH gamma antibody, PCDH-gamma, PCDHG, Protocadherin gamma , Protocadherin gamma, Gamma Protocadherin (pan), Pan-Gamma-Protocadherin, Pan Gamma Protocadherin
Background: The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. Anti-Protocadherin Gamma (pan) is ideal for research in Neuroscience, Cell Adhesion and Cell Signaling.
Gene Name: Protocadherin-Gamma-A1
-
基因ID
- 93709
-
UniProt
- Q91XZ0
抗原
-
