PCDHGA1 抗体 (AA 808-931) (Biotin)
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Quick Overview for PCDHGA1 抗体 (AA 808-931) (Biotin) (ABIN6657945)
抗原
See all PCDHGA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 808-931
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Supplier Product No.
- 200-306-w68
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Supplier
- Rockland
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原理
- Protocadherin Gamma (pan) Antibody Biotin
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交叉反应 （详细）
- BLAST analysis suggests that it is 99 % identical to human.
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纯化方法
- Anti-Protocadherin Gamma (pan) Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- Anti-Protocadherin Gamma (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 808-931 of mouse Protocadherin-gamma-A1 that is shared by all 22 Gamma-protocadherins.
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亚型
- IgG1
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anti-Protocadherin gamma A1 (PCDHGA1) (AA 241-340) antibody
PCDHGA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Protocadherin gamma A1 (PCDHGA1) (AA 287-315) antibodyPCDHGA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31763 unconjugated
anti-Protocadherin gamma A1 (PCDHGA1) (AA 294-323), (Middle Region) antibodyPCDHGA1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
Other: ICC/IF: 1:100
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说明
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Anti-Protocadherin Gamma (pan) Biotin Conjugated Antibody is tested for Western Blots and Immunocytochemistry. Expect a band approximately ~100 kDa on specific lysates or tissues. It will cross react with all Gamma-protocadherins -A, -B, and -C. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))
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别名
- Pcdhga1
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背景
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Synonyms: PCDH, Protocadherin Gamma antibody, PCDH gamma antibody, PCDH-gamma, PCDHG, Protocadherin gamma , Protocadherin gamma, Gamma Protocadherin (pan), Pan-Gamma-Protocadherin, Pan Gamma Protocadherin
Background: The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. Anti-Protocadherin Gamma (pan) is ideal for research in Neuroscience, Cell Adhesion and Cell Signaling.
Gene Name: Protocadherin-Gamma-A1
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基因ID
- 93709
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UniProt
- Q91XZ0
抗原
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