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KDM5B 抗体 (Internal Region)

This anti-KDM5B antibody is a 兔 多克隆 antibody detecting KDM5B in WB 和 ELISA. Suitable for 小鼠.
Rockland
产品编号 ABIN6657904
Supplier Product No.: 100-401-v92
发货至: 中国

Quick Overview for KDM5B 抗体 (Internal Region) (ABIN6657904)

抗原

See all KDM5B 抗体
KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

适用

  • 42
  • 21
  • 18
  • 1
  • 1
小鼠

宿主

  • 41
  • 7

克隆类型

  • 42
  • 6
多克隆

标记

  • 23
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KDM5B antibody is un-conjugated

应用范围

  • 37
  • 17
  • 16
  • 13
  • 13
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
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    Internal Region

    Supplier Product No.

    100-401-v92

    Supplier

    Rockland

    原理

    Jarid1b Antibody

    交叉反应 (详细)

    Cross reactivity with Jarid1b from other species not tested.

    纯化方法

    Anti-Jarid1b Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

    过滤

    Sterile filtered

    免疫原

    Anti-Jarid1b Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of mouse Jarid1b.

    亚型

    IgG
  • 应用备注

    ELISA_Dilution: 1:100 - 1:200

    Western_Blot_Dilution: 1:500

    说明

    Anti-Jarid1b Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 175 kDa in the appropriate cell lysate or extract.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: None

    Stabilizer: None

    Preservative: 0.05 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

    别名

    Jarid1b

    背景

    Synonyms: Lysine-specific demethylase 5B, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1

    Background: JARID1B is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor. Anti-Jarid1b Antibody is ideal for research in Epigenetics, Chromatin Remodeling and Cancer.

    Gene Name: Kdm5b

    基因ID

    10765

    NCBI登录号

    NP_006609

    UniProt

    Q80Y84

    途径

    Warburg Effect
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