KDM5B 抗体 (Internal Region)
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北京 101111
Quick Overview for KDM5B 抗体 (Internal Region) (ABIN6657904)
抗原
See all KDM5B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 100-401-v92
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Supplier
- Rockland
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原理
- Jarid1b Antibody
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交叉反应 （详细）
- Cross reactivity with Jarid1b from other species not tested.
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纯化方法
- Anti-Jarid1b Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
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过滤
- Sterile filtered
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免疫原
- Anti-Jarid1b Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of mouse Jarid1b.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibody
KDM5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7H3D7 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 65-165) antibodyKDM5B 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 784-883) antibodyKDM5B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) antibodyKDM5B 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F12 unconjugated
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应用备注
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ELISA_Dilution: 1:100 - 1:200
Western_Blot_Dilution: 1:500
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说明
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Anti-Jarid1b Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 175 kDa in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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别名
- Jarid1b
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背景
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Synonyms: Lysine-specific demethylase 5B, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1
Background: JARID1B is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor. Anti-Jarid1b Antibody is ideal for research in Epigenetics, Chromatin Remodeling and Cancer.
Gene Name: Kdm5b
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基因ID
- 10765
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NCBI登录号
- NP_006609
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UniProt
- Q80Y84
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途径
- Warburg Effect
抗原
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