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CD19 抗体 (PE)

This 大鼠 单克隆 antibody specifically detects CD19 in FACS. It exhibits reactivity toward 小鼠.
Rockland
产品编号 ABIN6657888
Supplier Product No.: 200-508-m72
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD19 抗体 (PE) (ABIN6657888)

抗原

See all CD19 抗体
CD19 (CD19 Molecule (CD19))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD19 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

1D3
  • Supplier Product No.

    200-508-m72

    Supplier

    Rockland

    原理

    CD19 Phycoerythrin Antibody

    交叉反应 (详细)

    Reactivity is observed against mouse CD19.

    纯化方法

    Phycoerythrin conjugated CD19 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against mouse CD19.

    过滤

    Sterile filtered

    免疫原

    Anti-CD19 Antibody (Monoclonal) was produced by repeated immunizations with mouse CD19 transfected cell line.

    亚型

    IgG2a kappa

    Labeling Ratio

    1-2
  • 应用备注

    Optional[Neutralization_Dilution]: 0.25-1 μg/10^6 cells

    说明

    Anti-CD19 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.1 % Gelatin

    Preservative: 0.09 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

    有效期

    6 months
  • 抗原

    CD19 (CD19 Molecule (CD19))

    别名

    CD19

    背景

    Synonyms: B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19

    Background: CD19 is a member of the immunoglobulin superfamily with 556 amino acid and two immunoglobulin-like C2-type domains. As a cell surface protein, CD19 is known to form a complex with CD21, CD81 and CD225 in the membrane of mature B cells. A major function of CD100 is to assemble with the antigen receptor of B lymphocytes so as to decrease the threshold for antigen receptor dependent stimulation thus enhancing the specificity and sensitivity of B cells towards antigens. Thus CD19 is an important protein for B cell antigen receptor signaling and regulation and also acts as a specialized adaptor protein for the amplification of Src family needed for this purpose. Regulation of growth of B cells is a major function of CD19 and its expression is confined to only B lymphocytes and follicular dendritic cells of the hematopoietic system. Increased expression of CD19 induces the production of auto-antibody thus giving an insight to the regulatory role of CD19 in autoimmunity. Defects in CD19 are a cause of hypogammaglobulinemia.

    Gene Name: Cd19

    基因ID

    12478

    NCBI登录号

    NP_033974

    UniProt

    P25918

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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