CD19 抗体 (PE)
Quick Overview for CD19 抗体 (PE) (ABIN6657888)
抗原
See all CD19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
Supplier Product No.
- 200-508-m72
-
Supplier
- Rockland
-
原理
- CD19 Phycoerythrin Antibody
-
交叉反应 （详细）
- Reactivity is observed against mouse CD19.
-
纯化方法
- Phycoerythrin conjugated CD19 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against mouse CD19.
-
过滤
- Sterile filtered
-
免疫原
- Anti-CD19 Antibody (Monoclonal) was produced by repeated immunizations with mouse CD19 transfected cell line.
-
亚型
- IgG2a kappa
-
Labeling Ratio
- 1-2
-
-
anti-CD19 Molecule (CD19) (AA 151-250) antibody
CD19 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 20-291) antibodyCD19 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 8G11B7 unconjugated
anti-CD19 Molecule (CD19) (C-Term) antibodyCD19 适用: 人, 小鼠, 大鼠, 猴, 绵羊, Pig, Cow, 豚鼠, 兔, 犬, Avian, Cat, 小鸡, 驴, 山羊, Hamster, 马 WB 宿主: 山羊 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 485-556) antibodyCD19 适用: 人, 小鼠, 大鼠, 绵羊 FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (pTyr531) antibodyCD19 适用: 人, 小鼠 FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 96-281) antibodyCD19 适用: 人 FACS, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CD19-3116 unconjugated
anti-CD19 Molecule (CD19) antibodyCD19 适用: 人 FACS, WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 143-172) antibodyCD19 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 160-258) antibodyCD19 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 20-291) antibodyCD19 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4C6G1 unconjugated
-
-
应用备注
- Optional[Neutralization_Dilution]: 0.25-1 μg/10^6 cells
-
说明
-
Anti-CD19 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.1 % Gelatin
Preservative: 0.09 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
-
有效期
- 6 months
-
-
- CD19 (CD19 Molecule (CD19))
-
别名
- CD19
-
背景
-
Synonyms: B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19
Background: CD19 is a member of the immunoglobulin superfamily with 556 amino acid and two immunoglobulin-like C2-type domains. As a cell surface protein, CD19 is known to form a complex with CD21, CD81 and CD225 in the membrane of mature B cells. A major function of CD100 is to assemble with the antigen receptor of B lymphocytes so as to decrease the threshold for antigen receptor dependent stimulation thus enhancing the specificity and sensitivity of B cells towards antigens. Thus CD19 is an important protein for B cell antigen receptor signaling and regulation and also acts as a specialized adaptor protein for the amplification of Src family needed for this purpose. Regulation of growth of B cells is a major function of CD19 and its expression is confined to only B lymphocytes and follicular dendritic cells of the hematopoietic system. Increased expression of CD19 induces the production of auto-antibody thus giving an insight to the regulatory role of CD19 in autoimmunity. Defects in CD19 are a cause of hypogammaglobulinemia.
Gene Name: Cd19
-
基因ID
- 12478
-
NCBI登录号
- NP_033974
-
UniProt
- P25918
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
-
