WDR5 抗体 (Internal Region)
Quick Overview for WDR5 抗体 (Internal Region) (ABIN6657813)
抗原
See all WDR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 100-401-v89
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Supplier
- Rockland
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原理
- Wdr5 Antibody
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交叉反应 (详细)
- Cross reactivity with Wdr5 from other species not tested.
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纯化方法
- Anti-Wdr5 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
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过滤
- Sterile filtered
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免疫原
- Anti-Wdr5 Antibody was produced in rabbits by repeated immunizations with two synthetic peptides containing an amino acid sequence from the internal part of mouse Wdr5.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:100 - 1:500
Western_Blot_Dilution: 1:1,000
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说明
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Anti-Wdr5 Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 36 kDa in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- WDR5 (WD Repeat Domain 5 (WDR5))
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别名
- Wdr5
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背景
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Synonyms: WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WD repeat-containing protein BIG-3, Big, Big3
Background: Wdr5 belongs to the family of WD repeat proteins which are involved in different cellular processes such as cell cycle progression, signal transduction, apoptosis, and gene regulation. It is a component of the Set1A and Set1B histone H3 methylation complexes. These complexes methylate lysine 4 of H3, thereby activating gene transcription. Wdr5 interacts with H3 dimethyl K4, but not with tri or mono methylated H3K4. Anti-Wdr5 Antibody is ideal for research in Cell Cycle Control, Signal Transduction, Apoptosis, Epigenetics, Gene Expression and Cancer.
Gene Name: Wdr5
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基因ID
- 140858
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NCBI登录号
- NP_543124
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UniProt
- P61965
抗原
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