SETD1A 抗体 (Internal Region, N-Term)
Quick Overview for SETD1A 抗体 (Internal Region, N-Term) (ABIN6657812)
抗原
See all SETD1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region, N-Term
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Supplier Product No.
- 100-401-v94
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Supplier
- Rockland
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原理
- Setd1a Antibody
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交叉反应 (详细)
- Cross reactivity with Setd1a from other species not tested.
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纯化方法
- Anti-Setd1a Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
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过滤
- Sterile filtered
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免疫原
- Anti-Setd1a Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Setd1a: two containing an amino acid sequence from the N-terminal region of the protein and one containing an amino acid sequence from the internal region of the protein.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:100
Western_Blot_Dilution: 1:500
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说明
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Anti-Setd1a Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 186 kDa in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- SETD1A (SET Domain Containing 1A (SETD1A))
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别名
- Setd1a
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背景
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Synonyms: Histone-lysine N-methyltransferase SETD1A, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, hSET1A, Set1/Ash2 histone methyltransferase complex subunit SET1
Background: SETD1A is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1A shows a non-overlapping localization with SETD1B, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression. Anti-Setd1a Antibody is ideal for research in Epigenetics and Gene Expression.
Gene Name: SETD1A
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基因ID
- 9739
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NCBI登录号
- NP_055527
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UniProt
- E9PYH6
抗原
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