STXBP1 抗体 (pSer241)
Quick Overview for STXBP1 抗体 (pSer241) (ABIN6657792)
抗原
See all STXBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer241
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Supplier Product No.
- 600-401-x15
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Supplier
- Rockland
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原理
- Munc18-1 Phospho S241 Antibody
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交叉反应 (详细)
- Anti-Phospho-Ser241 Munc18-1 Antibody is directed against Munc18-1 protein phosphorylated at S421.
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纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
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过滤
- Sterile filtered
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免疫原
- Anti-Phospho-Ser241 Munc18-1 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser241 of mouse Munc-18-1 protein conjugated to KLH.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
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说明
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Anti-Phospho-Ser241 Munc18-1 Antibody is tested for Western Blots and is specific for the ~65 kDa Munc18-1 protein phosphorylated at Ser241. Immunolabeling is blocked by the treatment of the lysate with lambda phosphatase (30 minutes, 800 units / 1 mg protein). Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
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有效期
- 12 months
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- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
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别名
- Munc18-1
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背景
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Synonyms: Syntaxin-binding protein 1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A
Background: Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin. Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex. The function of Munc18-1 is thought to be regulated by phosphorylation. Munc18-1 pS241 Antibody is ideal for researchers interested in neuroscience research.
Gene Name: STXBP1
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基因ID
- 20910
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NCBI登录号
- NP_001107041
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UniProt
- O08599
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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