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BAT3 抗体 (C-Term)

Name: BAT3 抗体 (C-Term)
SKU: ABIN6657747
Availability: OutOfStock

This anti-BAT3 antibody is a 兔多克隆 antibody detecting BAT3 in WB 和 ELISA. Suitable for 小鼠. This Primary Antibody has been cited in 2+ publications.

Anti-Mouse Scythe/BAT3 Antibody - Western Blot. (BAT3 抗体 (C-Term))

1 image

(2 references)

产品编号 ABIN6657747

Supplier Product No.: 100-401-b63s

发货至: 中国

Quick Overview for BAT3 抗体 (C-Term) (ABIN6657747)

抗原

See all BAT3 抗体

BAT3 (Large Proline-Rich Protein BAT3 (BAT3))

适用

小鼠

宿主

兔

克隆类型

多克隆

标记

This BAT3 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

Discover our top product BAT3 Primary Antibody

抗原表位
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C-Term

Supplier Product No.

100-401-b63s

Supplier

Rockland

原理

Scythe/Bat3 Antibody

纯化方法

This product was prepared from monospecific antiserum by addition of Sodium azide to 0.01 % .

过滤

Sterile filtered

免疫原

This Bat3 Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the C-terminal portion of mouse Scythe/Bat3.

亚型

IgG
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-1126) antibody
BAT3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-1126) antibody
BAT3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibody
BAT3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 943-992) antibody
BAT3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-200) antibody
BAT3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (Internal Region) antibody
Verified BAT3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-200) antibody
BAT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibody
BAT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibody
BAT3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibody
BAT3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA_Dilution: User Optimized
Western_Blot_Dilution: 1:5,000 to 1:8,000

说明

This polyclonal antibody has been tested for use in western blotting and is specific for mouse Scythe/Bat3 and its isoforms. Specific conditions for reactivity should be optimized by the end user. Expect multiple bands, with the predominant at approximately 200kDa in size corresponding to Scythe/BAT3 by western blotting in the appropriate cell lysate or extract. In western blot analysis of endogenous protein, multiple bands of Scythe/BAT3 may appear corresponding to variable amount of splice isoforms present.

限制

仅限研究用
状态

Liquid

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

有效期

3 months
Desmots, Russell, Michel, McKinnon: "Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3264-71, (2008) (PubMed).

Desmots, Russell, Lee, Boyd, McKinnon: "The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development." in: Molecular and cellular biology, Vol. 25, Issue 23, pp. 10329-37, (2005) (PubMed).
抗原

BAT3 (Large Proline-Rich Protein BAT3 (BAT3))

别名

Scythe/Bat3

背景

Synonyms: rabbit anti-Bat3 Antibody, rabbit anti-Scythe Antibody, Bat3, HLA-B-associated transcript 3, Large proline-rich protein BAT3
Background: Scythe protein (also known as Bat3 and HLA-B-associated transcript 3) is an apoptotic regulator that is highly conserved in eukaryotes and contains a ubiquitin-like domain near its N-terminus. Scythe binds Reaper, a potent apoptotic inducer. Scythe and Reaper are thought to signal apoptosis, in part through regulating the folding and and activity of apoptotic signaling molecules. Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis. Scythe interacts with transforming growth factor-beta (TGF-beta) receptors and enhances TGF-beta1-induced type I collagen expression in mesangial cells. Scythe and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression. HLA-B-associated transcript 3 (Bat3/Scythe) is essential for p300-mediated acetylation of p53. Bat3 is identified as a critical regulator of Hsp70-2 in spermatogenesis, thereby providing a possible molecular target in idiopathic male infertility. The human Scythe/BAT3 ortholog in rodents is predominantly and developmentally expressed in testis.
Gene Name: BAT3

基因ID

224727, 33147082

UniProt

Q9Z1R2