LGI1 抗体 (AA 37-113)
Quick Overview for LGI1 抗体 (AA 37-113) (ABIN6657718)
抗原
See all LGI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 37-113
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Supplier Product No.
- 200-301-w73
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Supplier
- Rockland
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原理
- Lgi1 Antibody
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交叉反应 （详细）
- BLAST analysis suggests that it is 100 % identical to rat, 98 % identical to human and ~50 % identical to LGI2, LGI3, and LGI4.
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纯化方法
- Anti-LGI1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- Anti-Lgi1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 37-113 (LRRNT domain and first LRR repeat) of mouse Lgi1.
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亚型
- IgG2a
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anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 451-557) antibody
LGI1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibodyLGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 unconjugated
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (HRP)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 HRP
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (FITC)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 FITC
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (Biotin)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 Biotin
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (PE)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 PE
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (PerCP)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 PerCP
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (APC)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 APC
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (Atto 488)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 Atto 488
anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) (AA 37-113) antibody (Atto 594)LGI1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S283-7 Atto 594
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应用备注
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ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: User Optimized
Western_Blot_Dilution: 1:1000
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说明
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Anti-LGI1 Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~60kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
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别名
- LGI1
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背景
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Synonyms: ADLTE, ADPAEF, ADPEAF, Epitempin 1, EPT, ETL1, IB1099, leucine rich glioma inactivated 1, OTTHUMP00000020121, OTTHUMP00000020122
Background: The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist, this LGI1 antibody will recognize only the longer form. Anti-LGI1 is ideal for research in Neuroscience and Cancer.
Gene Name: LGI1
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基因ID
- 56839
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UniProt
- Q9JIA1
抗原
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