AHSA1 抗体
Quick Overview for AHSA1 抗体 (ABIN6657694)
抗原
See all AHSA1 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 100-401-e82
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Supplier
- Rockland
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原理
- Aha1 Antibody
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交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with Aha 1 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-Aha 1 Antibody was purified by Protein A chromatography.
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过滤
- Sterile filtered
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免疫原
- Aha1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with Mouse Aha1.
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亚型
- IgG
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应用备注
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Immunoprecipitation_Dilution: User Optimized
ELISA_Dilution: 1:200
Immunohistochemistry_Dilution: 1:1000
Western_Blot_Dilution: 0.5-1:1000
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说明
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Anti-Aha1 Antibody has been tested in western blot, ICC, and IHC and is suitable for use in ELISA, IF microscopy and IP. Expect a band approximately ~38kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Reconstructing the Hsp90/Tau Machine." in: Current enzyme inhibition, Vol. 9, Issue 1, pp. 41-45, (2013) (PubMed).
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: "Reconstructing the Hsp90/Tau Machine." in: Current enzyme inhibition, Vol. 9, Issue 1, pp. 41-45, (2013) (PubMed).
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- AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))
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别名
- Aha1
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背景
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Synonyms: Aha1, SHSA1, HspC322, p38, Activator of 90 kDa heat shock protein ATPase homolog 1
Background: Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding. It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors.
Gene Name: Ahsa1
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基因ID
- 217737
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NCBI登录号
- NP_666148
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UniProt
- Q8BK64
抗原
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