RPS6 抗体 (pSer244)
Quick Overview for RPS6 抗体 (pSer244) (ABIN6657597)
抗原
See all RPS6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer244
-
Supplier Product No.
- 600-401-x26
-
Supplier
- Rockland
-
原理
- Ribosomal protein S6 Phospho S244 Antibody
-
交叉反应 （详细）
- Anti-Phospho-Ser244 Ribosomal Protein S6 Antibody is directed against Ribosomal Protein S6 phosphorylated at S244.
-
纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
-
过滤
- Sterile filtered
-
免疫原
- Anti-Phospho-Ser244 Ribosomal Protein S6 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding the phospho-Ser244 of mouse rpS6 conjugated to KLH.
-
亚型
- IgG
-
-
anti-Ribosomal Protein S6 (RPS6) antibody
RPS6 适用: 人, 大鼠 WB, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 981CT2-1-1 unconjugated
anti-Ribosomal Protein S6 (RPS6) (AA 1-100) antibodyRPS6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 (RPS6) antibodyRPS6 适用: 人, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 小鼠 Monoclonal 981CT2-1-1 unconjugated
anti-Ribosomal Protein S6 (RPS6) (AA 151-249) antibodyRPS6 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 (RPS6) (Thr826) antibodyRPS6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 (RPS6) (AA 13-52), (N-Term) antibodyRPS6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 (RPS6) (AA 220-249) antibodyRPS6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 (RPS6) (AA 227-257) antibodyRPS6 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 (RPS6) (pSer235), (pSer236) antibodyRPS6 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 (RPS6) (AA 35-229) antibodyRPS6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
-
说明
-
Anti-Ribosomal Protein S6 pS244 Antibody is tested for Western Blots and is specific for the ~28 kDa rpS6 protein phosphorylated at Ser244. Specific conditions for reactivity should be optimized by the end user.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
-
储存条件
- -20 °C
-
储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
-
有效期
- 12 months
-
-
- RPS6 (Ribosomal Protein S6 (RPS6))
-
别名
- Ribosomal protein S6
-
背景
-
Synonyms: 40S ribosomal protein S6, Phosphoprotein NP33, rpS6
Background: Ribosomal protein S6 (rpS6) is a critical component of the 40 S ribosomal subunit that mediates translation initiation at the 5'-m7GpppG cap of mRNA. The rpS6 protein is both cytoplasmic and nuclear localized . In response to mitogenic stimuli, rpS6 undergoes ordered C-terminal phosphorylation by p70 S6 kinases and p90 ribosomal S6 kinases on four Ser residues (Ser-235, Ser-236, Ser-240, and Ser-244) whose modification potentiates rpS6 cap binding activity. Additionally, rpS6 phosphorylation and function are highly regulated and have been implicated in the regulation of translational initiation and protein synthesis in response to extracellular stimuli such as TRAIL and gamma interferon (IFN-γ), as well as upon activation of the phosphatidylinositol 3-kinase (PI3K)-Akt-mTOR pathway. Ribosomal Protein S6 pS244 Antibody is ideal for researchers interested in neuroscience research.
Gene Name: RPS6
-
基因ID
- 20104
-
NCBI登录号
- NP_033122
-
UniProt
- P62754
-
途径
- Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
-
