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SLC22A6 抗体 (C-Term)

This anti-SLC22A6 antibody is a 兔 多克隆 antibody detecting SLC22A6 in WB 和 IHC. Suitable for 人.
Rockland
产品编号 ABIN6657539
Supplier Product No.: 600-401-r18
发货至: 中国

Quick Overview for SLC22A6 抗体 (C-Term) (ABIN6657539)

抗原

See all SLC22A6 抗体
SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

适用

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宿主

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克隆类型

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多克隆

标记

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This SLC22A6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    Supplier Product No.

    600-401-r18

    Supplier

    Rockland

    原理

    SLC22A6/OAT1 Antibody

    交叉反应 (详细)

    Anti-SLC22A6/OAT1 antibody is directed against human SLC22A6/OAT1 protein.

    纯化方法

    The product was affinity purified from monospecific antiserum by immunoaffinity purification.

    免疫原

    SLC22A6/OAT1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human SLC22A6/OAT1.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry_Dilution: 1:100-1:500

    Western_Blot_Dilution: 0.5 μg/mL

    说明

    Anti-SLC22A6/OAT1 is tested for Immunohistochemistry -P and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~61.8 kDa corresponding to the appropriate cell lysate or extract.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 100 μL

    缓冲液

    Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

    Stabilizer: 5 mg BSA

    Preservative: 0.05 mg Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

    别名

    SLC22A6/OAT1

    背景

    Synonyms: Organic anion transporter 1,

    Background: SLC22A6(Solute carrier family 22 (organic anion transporter), member 6), also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. The SLC22A6 gene is mapped on 11q12.3. It plays a central role in renal organic anion transport. Along with OAT3, OAT1 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. The SLC22A6 gene contains 10 exons and spans 8.2 kb. OAT1 functions as organic anion exchanger. When the uptake of one molecule of an organic anion is transported into a cell by an OAT1 exchanger, one molecule of an endogenous dicarboxylic acid (such as glutarate, ketoglutarate, etc) is simultaneously transported out of the cell. PAH uptake in Xenopus oocytes injected with OAT1 mRNA was demonstrated by Race et al. This antibody is suitable for researchers interested in cancer research.

    Gene Name: SLC22A6

    基因ID

    9356

    NCBI登录号

    NP_004781

    UniProt

    Q4U2R8

    途径

    Dicarboxylic Acid Transport
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