SLC22A6 抗体 (C-Term)
Quick Overview for SLC22A6 抗体 (C-Term) (ABIN6657539)
抗原
See all SLC22A6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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Supplier Product No.
 - 600-401-r18
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Supplier
 - Rockland
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原理
 - SLC22A6/OAT1 Antibody
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交叉反应 (详细)
 - Anti-SLC22A6/OAT1 antibody is directed against human SLC22A6/OAT1 protein.
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纯化方法
 - The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
 - SLC22A6/OAT1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human SLC22A6/OAT1.
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亚型
 - IgG
 
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应用备注
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Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 0.5 μg/mL
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说明
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Anti-SLC22A6/OAT1 is tested for Immunohistochemistry -P and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~61.8 kDa corresponding to the appropriate cell lysate or extract.
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限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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缓冲液
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal - 
                                            
储存液
 - Thimerosal (Merthiolate)
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注意事项
 - This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
 - 12 months
 
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- SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))
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别名
 - SLC22A6/OAT1
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背景
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Synonyms: Organic anion transporter 1,
Background: SLC22A6(Solute carrier family 22 (organic anion transporter), member 6), also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. The SLC22A6 gene is mapped on 11q12.3. It plays a central role in renal organic anion transport. Along with OAT3, OAT1 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. The SLC22A6 gene contains 10 exons and spans 8.2 kb. OAT1 functions as organic anion exchanger. When the uptake of one molecule of an organic anion is transported into a cell by an OAT1 exchanger, one molecule of an endogenous dicarboxylic acid (such as glutarate, ketoglutarate, etc) is simultaneously transported out of the cell. PAH uptake in Xenopus oocytes injected with OAT1 mRNA was demonstrated by Race et al. This antibody is suitable for researchers interested in cancer research.
Gene Name: SLC22A6
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基因ID
 - 9356
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NCBI登录号
 - NP_004781
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UniProt
 - Q4U2R8
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途径
 - Dicarboxylic Acid Transport
 
抗原
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