PIK3R2 抗体 (Internal Region)
Quick Overview for PIK3R2 抗体 (Internal Region) (ABIN6657522)
抗原
See all PIK3R2 (PI3K p85b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 600-401-r17
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Supplier
- Rockland
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原理
- PIK3R2 Antibody
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交叉反应 （详细）
- Anti-PIK3R2 antibody is directed against human PIK3R2 protein.
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- PIK3R2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human PIK3R2.
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亚型
- IgG
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anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-60) antibody
PI3K p85b 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 75-125), (Regulatory Subunit beta) antibodyPI3K p85b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠, Cow, 犬 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Subunit beta) antibodyPI3K p85b 适用: 人, Cow, 猴 WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal T15 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Thr232) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 430-470) antibodyPI3K p85b 适用: 人 WB 宿主: 兔 Polyclonal RB48985 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Tyr467) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 447-461), (Middle Region) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 445-474) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13091 unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 0.5 μg/mL
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说明
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Anti-PIK3R2 is tested for Immunohistochemistry -P and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~81.5 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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缓冲液
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal -
储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
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别名
- PIK3R2
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背景
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Synonyms: Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta,
Background: PIK3R2(Phosphatidylinositol 3-kinase, regulatory subunit 2), also called p85-Beta, is an enzyme that in humans is encoded by the PIK3R2 gene. The PIK3R2 gene is mapped on 19p13.11. The NS1 protein from various influenza strains also bound p85-beta, but not p85-alpha. Binding of p85-beta and activation of PI3K required tyr89 of NS1, and mutant viruses expressing NS1 with a tyr89-to-phe substitution grew more slowly in cell culture than wildtype viruses. Using mouse embryonic fibroblasts, Park et al. showed that, in addition to regulating PI3K function, p85-alpha and p85-beta regulated the function of Xbp1s, a transcription factor that orchestrates the unfolded protein response (UPR) following endoplasmic reticulum (ER) stress. Overexpression of PIK3R2 in livers of ob/ob mice increased glucose tolerance and reduced blood glucose concentrations. This antibody is suitable for researchers interested in cancer research.
Gene Name: PIK3R2
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基因ID
- 5296
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NCBI登录号
- NP_005018
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UniProt
- O00459
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途径
- VEGF Signaling, BCR Signaling
抗原
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