MUC5B 抗体
Quick Overview for MUC5B 抗体 (ABIN6657491)
抗原
See all MUC5B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
Supplier Product No.
- 200-301-p41
-
Supplier
- Rockland
-
原理
- Mucin Gastric Antibody
-
交叉反应 (详细)
- This product reacts with human, mouse, rat, and rabbit.
-
纯化方法
- Anti-Mucin Gastric antibody was purified from mouse ascites by protein A chromatography.
-
免疫原
- Mucin Gastric antibody was produced in mice by repeated immunizations with mucin from human ovarian cyst fluid.
-
亚型
- IgG1
-
-
-
-
应用备注
-
ELISA_Dilution: 1:20,000
Immunohistochemistry_Dilution: 2-4 μg/mL
Western_Blot_Dilution: 1-2 μg/mL
Other: ICC: 1 μg/mL
-
说明
-
Anti-Mucin Gastric is tested for Immunocytochemistry, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~596 kDa corresponding to the appropriate cell lysate or extract.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
-
Reconstitution_Buffer: Neutral PBS
Reconstitution_Volume: 1.0 mL
-
缓冲液
-
Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- MUC5B (Mucin 5 Subtype B (MUC5B))
-
别名
- MUC5B
-
背景
-
Synonyms: MG1, MUC5, MUC9, MUC-5B, Cervical mucin, High molecular weight salivary mucin MG1, Mucin-5 subtype B, tracheobronchial, Sublingual gland mucin
Background: MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90 % breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. This antibody is suitable for researchers interested in neuroscience research, developmental signaling, and cell adheshion.
Gene Name: MUC5B
-
基因ID
- 727897
-
NCBI登录号
- NP_002449
-
UniProt
- Q9HC84
抗原
-