Caldesmon 抗体
Quick Overview for Caldesmon 抗体 (ABIN6657487)
抗原
See all Caldesmon (CALD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-p24
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Supplier
- Rockland
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原理
- Caldesmon (smooth) Antibody
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交叉反应 (详细)
- This product reacts with human, mouse, and rabbit.
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纯化方法
- Anti-Caldesmon antibody was purified from mouse ascites by protein A chromatography.
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过滤
- Sterile filtered
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免疫原
- Caldesmon (smooth) antibody was produced in mice by repeated immunizations with human uterus smooth muscle extract.
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亚型
- IgG1
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应用备注
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ELISA_Dilution: 1:20,000
Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 1-2 μg/mL
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说明
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Anti-Caldesmon is tested for Immunohistochemistry -P and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~93.2 kDa with isoforms ~60kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
- Caldesmon (smooth)
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背景
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Synonyms: CDM, H-CAD, L-CAD
Background: Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells. The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons. This antibody is suitable for researchers interested in neurodegenerative diseases, developmental signaling, GPCR signaling, and MAK Kinase Signaling.
Gene Name: CALD1
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基因ID
- 800
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NCBI登录号
- NP_004333
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UniProt
- Q05682
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途径
- Myometrial Relaxation and Contraction
抗原
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