STX1A 抗体
Quick Overview for STX1A 抗体 (ABIN6657443)
抗原
See all STX1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-e40
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Supplier
- Rockland
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原理
- Syntaxin Antibody
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交叉反应 (详细)
- Anti-Syntaxin Monoclonal Antibody is directed against Syntaxin.
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纯化方法
- Syntaxin antibody was purified by Protein G chromatography from cell culture supernatant.
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免疫原
- Anti-Syntaxin Monoclonal Antibody was produced in mouse by repeated immunizations with Synaptic immunoprecipitate (crude) from human brain.
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亚型
- IgG1
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应用备注
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Immunohistochemistry_Dilution: 1:100
Western_Blot_Dilution: 1:1000
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说明
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Anti-Syntaxin antibody is suitable for use in Western Blotting and IHC. Expect a band or approximately 36 kDa in size corresponding to syntaxin proteins in Western blot of rat brain lysate. Tested for use in immunohistochemistry on formalin fixed, vibratome sections. Does not work on paraffin sections. Researchers should determine optimal titers for applications that are not stated below.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- STX1A (Syntaxin 1A (Brain) (STX1A))
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别名
- STX1A
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背景
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Synonyms: Neuron-specific antigen HPC-1, Syntaxin-1A
Background: Syntaxin antibody detects Syntaxin-1A protein which is part of a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia. Anti-Syntaxin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: STX1A
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基因ID
- 6804
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UniProt
- Q16623
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途径
- Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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