PCLO 抗体
Quick Overview for PCLO 抗体 (ABIN6657442)
抗原
See all PCLO 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-g30
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Supplier
- Rockland
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原理
- Piccolo Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Piccolo from human, mouse, rat based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-Piccolo Antibody was purified by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- Piccolo Antibody was produced in mice by repeated immunizations raised against a full length protein.
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亚型
- IgG2b kappa
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anti-Piccolo (Presynaptic Cytomatrix Protein) (PCLO) antibody (PE)
PCLO 适用: 人 ICFC 宿主: 小鼠 Monoclonal PCLO-01 PE
anti-Piccolo (Presynaptic Cytomatrix Protein) (PCLO) (AA 1-356) antibodyPCLO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Piccolo (Presynaptic Cytomatrix Protein) (PCLO) antibodyPCLO 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal PCLO-01 unconjugated
anti-Piccolo (Presynaptic Cytomatrix Protein) (PCLO) antibodyPCLO 适用: 人 WB, IHC, FM 宿主: 兔 Polyclonal unconjugated
anti-Piccolo (Presynaptic Cytomatrix Protein) (PCLO) (C-Term) antibodyPCLO 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, Pig, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:200
IF_Microscopy_Dilution: 1:100
Western_Blot_Dilution: 1:1000
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说明
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Anti-Piccolo Antibody is tested for use in WB, ICC/IF, and ELISA. Expect a band ~550kDa in specific lysate or tissue samples. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
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别名
- PCLO
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背景
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Synonyms: ACZ Antibody, Aczonin Antibody, PCLO Antibody, Pico Antibody, presynaptic cytomatrix protein Antibody, protein piccolo, Brain-derived HLMN protein, Multidomain presynaptic cytomatrix protein
Background: Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1.
Gene Name: Pclo
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基因ID
- 27445
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NCBI登录号
- NP_055325
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UniProt
- Q9Y6V0
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途径
- Hormone Transport, Synaptic Vesicle Exocytosis
抗原
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