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THRA 抗体 (N-Term)

This anti-THRA antibody is a 小鼠 单克隆 antibody detecting THRA in WB. Suitable for 人.
Rockland
产品编号 ABIN6657362
Supplier Product No.: 209-301-e44
发货至: 中国

Quick Overview for THRA 抗体 (N-Term) (ABIN6657362)

抗原

See all THRA 抗体
THRA (Thyroid Hormone Receptor, alpha (THRA))

适用

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宿主

  • 59
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  • 1
小鼠

克隆类型

  • 60
  • 28
单克隆

标记

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This THRA antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

1330
  • 抗原表位

    • 16
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    • 1
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    N-Term

    Supplier Product No.

    209-301-e44

    Supplier

    Rockland

    原理

    Thyroid Hormone Receptor alpha 2 Antibody

    交叉反应 (详细)

    Thyroid Hormone Receptor alpha 2 antibodies are purified by Protein G chromatography from cell culture supernatant.

    纯化方法

    Anti-Thyroid Hormone Receptor alpha 2 Monoclonal Antibody is directed against human thyroid hormone receptor alpha 2 protein.

    免疫原

    Anti-Thyroid Hormone Receptor alpha 2 Monoclonal Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region of Thyroid Hormone Receptor alpha 2.

    亚型

    IgG1
  • 应用备注

    Optional[Neutralization_Dilution]: 1:1000

    说明

    Anti-Thyroid Hormone Receptor alpha 2 antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band or approximately 58 kDa in size corresponding to TR-α2 proteins in the appropriate cell lysate or extract.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    THRA (Thyroid Hormone Receptor, alpha (THRA))

    别名

    Thyroid Hormone Receptor alpha 2

    背景

    Synonyms: mouse anti-Thyroid Hormone Receptor alpha 2 Antibody, mouse anti-Thra antibody, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha

    Background: Thyroid Hormone Receptor alpha 2 antibody detects TRα2. Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors, TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain. Anti-TRα2 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

    Gene Name: THRA

    基因ID

    7067

    NCBI登录号

    NP_001177848

    UniProt

    P10827

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development
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