THRA 抗体 (N-Term)
Quick Overview for THRA 抗体 (N-Term) (ABIN6657362)
抗原
See all THRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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Supplier Product No.
- 209-301-e44
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Supplier
- Rockland
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原理
- Thyroid Hormone Receptor alpha 2 Antibody
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交叉反应 (详细)
- Thyroid Hormone Receptor alpha 2 antibodies are purified by Protein G chromatography from cell culture supernatant.
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纯化方法
- Anti-Thyroid Hormone Receptor alpha 2 Monoclonal Antibody is directed against human thyroid hormone receptor alpha 2 protein.
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免疫原
- Anti-Thyroid Hormone Receptor alpha 2 Monoclonal Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region of Thyroid Hormone Receptor alpha 2.
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亚型
- IgG1
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-Thyroid Hormone Receptor alpha 2 antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band or approximately 58 kDa in size corresponding to TR-α2 proteins in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- THRA (Thyroid Hormone Receptor, alpha (THRA))
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别名
- Thyroid Hormone Receptor alpha 2
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背景
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Synonyms: mouse anti-Thyroid Hormone Receptor alpha 2 Antibody, mouse anti-Thra antibody, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha
Background: Thyroid Hormone Receptor alpha 2 antibody detects TRα2. Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors, TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain. Anti-TRα2 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: THRA
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基因ID
- 7067
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NCBI登录号
- NP_001177848
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UniProt
- P10827
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development
抗原
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