Retinoic Acid Receptor alpha 抗体 (N-Term)
Quick Overview for Retinoic Acid Receptor alpha 抗体 (N-Term) (ABIN6657357)
抗原
See all Retinoic Acid Receptor alpha (RARA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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Supplier Product No.
- 209-301-e25
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Supplier
- Rockland
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原理
- Retinoic Acid Receptor alpha Antibody
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交叉反应 (详细)
- Retinoic Acid Receptor alpha antibody was Protein G purified from cell culture supernatant.
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纯化方法
- Anti-Retinoic Acid Receptor alpha antibody detects Retinoic Acid Receptor alpha.
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免疫原
- Anti-Retinoic Acid Receptor alpha was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the N-terminal region of RAR-alpha.
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亚型
- IgG1
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-Retinoic Acid Receptor alpha antibody is tested for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to expected molecular weight for RAR-α proteins in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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别名
- Retinoic Acid Receptor alpha
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背景
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Synonyms: mouse anti-Retinoic Acid Receptor alpha Antibody, mouse anti-RAR-alpha antibody, RAR-alpha, Nuclear receptor subfamily 1 group B member 1, NR1B1, Retinoic Acid Receptor, α-Isotype
Background: Retinoic Acid Receptor alpha antibody detects RAR alpha. Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
Gene Name: RARA
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基因ID
- 5914
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UniProt
- P10276
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
抗原
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